Regenerative Medicine

Istituto Ortopedico Galeazzi

key figures 

CLINICAL SERVICES:

  • Conservative Osteoarthritis Treatment   
  • Conservative Tendinopathy Treatment
  • Conservative Muscle Lesion Treatment
  • Oral Tissue Regeneration

RE.GA.IN is a centre of excellence that provides a clinical platform to ensure the best experience in regenerative medicine. Patients' data are collected longitudinally through the most modern standard operative procedure and then interpreted to identify the most performing treatment for a given indication. REGAIN treats the patients only with selected medical devices, paying attention to their scientific quality and safety profile. RE.GA.IN activities are supported by the Research Laboratories of the Galeazzi Research Hospital to ensure a full characterization of the biological products produced in a custom manner for each patient.

 

treatmentS

Joint Degeneration

The biological treatments performed at RE.GA.IN are indicated in those patients who suffer from joint pain related to cartilage degeneration. Both early or severe joint diseases can benefit from these treatments given their anti-inflammatory properties. Indeed, biological products contain cells and/or molecules able to restore the joint homeostasis with direct clinical and functional benefits. The treatments are non–invasive and in case of failure do not impede any further treatment/therapy. All the biological products are prepared from portion of tissue belonging to the patient (autologous treatment, donor = recipient) and prepared according to the highest standard of quality required for these procedures. The devices used at RE.GA.IN to obtain these products have been selected accurately by a panel of expert basing on their clinic efficacy as reported in literature. The biological products are used both alone as injective treatments or in association with intra-articular surgical procedures for cartilage repair. These treatments are indicated in patients of all ages, although literature report better outcomes in the youngest ones.

Main Pathologies Treated:

  • Diffuse chondral lesion
  • Osteoarthritis (all stages)

Top Procedures:

  • PRP (Platelet Rich Plasma)
  • PRGF (Platelet Rich Growth Factors)
  • BMAC (Bone Marrow Aspirate Concentrate)
  • Adipose tissue concentrate (µFAT and SVF) injection for knee, ankle, shoulder and spine

The surgical activity also includes the treatment of patients with degenerative pathology of the spine, including the primary and secondary arthritis of scoliosis, to rheumatoid arthritis, the post-surgical pathology, the whole degenerative pathology of the hip and the knee.

Tendon Degenerations

The biological treatments performed at RE.GA.IN are indicated in those patients who suffer from both chronic and acute tendon disorders. The rationale behind their use is related to the immunomodulatory and inflammatory power which characterize the cells and molecules contained in the biological products. Cells and molecules act as mediators, restoring the tissue homeostasis with direct functional and clinical benefits for the patients. The treatments are non–invasive and in case of failure do not impede any further treatment/therapy. All the biological products are prepared from portion of tissue belonging to the patient (autologous treatment, donor = recipient) and prepared according to the highest standard of quality required for these procedures. The devices used at RE.GA.IN to obtain these products have been selected accurately by a panel of expert basing on their clinic efficacy as reported in literature. The biological products are used both alone as injective treatments or in association with surgical procedures for tendon repair. These treatments are indicated in patients of all ages, although literature report better outcomes in the youngest ones.

Main Pathologies Treated:

  • Tendinopathy (all stages)
  • Partial tendon rupture

Top Procedures:

  • PRP (Platelet Rich Plasma)
  • PRGF (Platelet Rich Growth Factors)
  • BMAC (Bone Marrow Aspirate Concentrate)
  • Adipose tissue concentrate (µFAT and SVF) injection

Oral tissue Regeneration

The biological treatments performed at RE.GA.IN are indicated in those patients who suffer from oral bone and periodontal tissues impairment. PRP (Platelet Rich Plasma) and PRGF (Plasma Rich in Growth Factors) are the most widely used given their ability to promote and conduct tissue regeneration in cases where the intrinsic repair ability is compromised, especially in aging patients. In particular the molecules interact with the resident cells improving their viability and specific functions. The treatments are non–invasive and in case of failure do not impede any further treatment/therapy. All the biological products are prepared from portion of tissue belonging to the patient (autologous treatment, donor = recipient) and prepared according to the highest standard of quality required for these procedures. The devices used at RE.GA.IN to obtain these products have been selected accurately by a panel of expert basing on their clinic efficacy as reported in literature. The biological products are used in association with oral surgical procedures, such as the treatment of alveolar socket after tooth extractions, and to improve bone quality before implantation alone or in association with bone substitutes. The biological treatments are indicated in patients of all ages, although literature report better outcomes in the youngest ones.

Main Pathologies Treated:

  • Periodontal procedures
  • Druginduced osteonecrosis

Top Procedures:

  • PRP (Platelet Rich Plasma) and PRGF (Platelet Rich Growth Factors) application alone or in association with bone substitutes

 

NOTABLE ADVANCED TECHNOLOGICAL EQUIPMENT

  • Fullyequipped rooms for regenerative medicine treatments
  • High-quality disposable medical devices for PRP and cell concentrate production