Mario Gramegna

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Specialty:

Cardiology

Profession:

Cardiologist

Location:

Department of Cardiothoracic Anesthesia and Intensive Care @ Ospedale San Raffaele

Languages:

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Biography

Dr. Mario Gramegna is a cardiologist at the Cardiac and Cardiovascular Intensive Care Unit of IRCCS Ospedale San Raffaele in Milan, led by Prof. Alberto Zangrillo. Additionally, he serves as a cardiology consultant for Casa di Cura La Madonnina.

After graduating with honors in Medicine and Surgery from the Università Cattolica del Sacro Cuore in 2013, he completed his specialization with honors in Cardiovascular Diseases at Vita-Salute San Raffaele University in 2019. During his studies, he completed a training period abroad at the Royal Brompton Hospital in London and Harefield Hospital in the UK.

In his clinical practice, Dr. Gramegna focuses on treating cardiological emergencies, particularly acute myocardial infarction, acute heart failure, and cardiogenic shock. He also provides care to patients requiring mechanical circulatory support (such as intra-aortic balloon pumps and Impella devices) and those with ventricular assist devices (LVADs). He performs outpatient cardiology services, addressing common conditions like hypertension, chronic heart failure, coronary artery disease, valvular heart disease, atrial fibrillation, and other cardiac arrhythmias, as well as venous thromboembolism.

Dr. Gramegna also serves as a clinical tutor for medical students at Vita-Salute San Raffaele University in Milan and has delivered lectures in the Cardiovascular Disease Specialization program. He is a member of the Young ACVC (Acute CardioVascular Care Association) Community of the European Society of Cardiology.

He has authored and co-authored over 40 publications in national and international scientific journals and contributed to several book chapters. His h-index is 15, and he regularly participates in national and international scientific congresses as a speaker.

Publications

Latest publications

Anticoagulation for Percutaneous Ventricular Assist Device-Supported Cardiogenic Shock: JACC Review Topic of the Week

J Am Coll Cardiol. 2022 May 17;79(19):1949-1962. doi: 10.1016/j.jacc.2022.02.052.

Vandenbriele C, Arachchillage DJ, Frederiks P, Giustino G, Gorog DA, Gramegna M, Janssens S, Meyns B, Polzin A, Scandroglio M, Schrage B, Stone GW, Tavazzi G, Vanassche T, Vranckx P, Westermann D, Price S, Chieffo A.

Joint EAPCI/ACVC expert consensus document on percutaneous ventricular assist devices

EuroIntervention. 2021 Jul 20;17(4):e274-e286. doi: 10.4244/EIJY21M05_01

Chieffo A, Dudek D, Hassager C, Combes A, Gramegna M, Halvorsen S, Huber K, Kunadian V, Maly J, Møller JE, Pappalardo F, Tarantini G, Tavazzi G, Thiele H, Vandenbriele C, Van Mieghem N, Vranckx P, Werner N, Price S.

Intra-Aortic Balloon Pumping in Acute Decompensated Heart Failure With Hypoperfusion: From Pathophysiology to Clinical Practice

Circ Heart Fail. 2021 Nov;14(11):e008527. doi: 10.1161/CIRCHEARTFAILURE.121.008527

Baldetti L, Pagnesi M, Gramegna M, Belletti A, Beneduce A, Pazzanese V, Calvo F, Sacchi S, Van Mieghem NM, den Uil CA, Metra M, Cappelletti AM.

Longitudinal Invasive Hemodynamic Assessment in Patients With Acute Decompensated Heart Failure-Related Cardiogenic Shock: A Single-Center Experience

Circ Heart Fail. 2022 Feb;15(2):e008976. doi: 10.1161/CIRCHEARTFAILURE.121.008976.

Baldetti L, Sacchi S, Pazzanese V, Calvo F, Gramegna M, Barone G, Boccellino A, Pagnesi M, Cappelletti AM.

ST-Segment-Elevation Myocardial Infarction During COVID-19 Pandemic: Insights From a Regional Public Service Healthcare Hub

Circ Cardiovasc Interv. 2020 Aug;13(8):e009413.

Gramegna M, Baldetti L, Beneduce A, Pannone L, Falasconi G, Calvo F, Pazzanese V, Sacchi S, Pagnesi M, Moroni F, Ajello S, Melisurgo G, Agricola E, Camici PG, Scandroglio AM, Landoni G, Ciceri F, Zangrillo A, Cappelletti AM.

Impella RP support in refractory right ventricular failure complicating acute myocardial infarction with unsuccessful right coronary artery revascularization

Int J Cardiol. 2020 Mar 1;302:135-137.

Gramegna M, Beneduce A, Bertoldi LF, Pagnesi M, Marini C, Pazzanese V, Camici PG, Chieffo A, Pappalardo F.

Use of extracorporeal membrane oxygenation in high-risk acute pulmonary embolism: A systematic review and meta-analysis

Artif Organs. 2021 Jun;45(6):569-576.

Baldetti L, Beneduce A, Cianfanelli L, Falasconi G, Pannone L, Moroni F, Venuti A, Sacchi S, Gramegna M, Pazzanese V, Calvo F, Gallone G, Pagnesi M, Cappelletti AM.

Collateral Damage: Medical Care Avoidance Behavior Among Patients With Myocardial Infarction During the COVID-19 Pandemic

JACC Case Rep. 2020 Aug;2(10):1620-1624.

Moroni F, Gramegna M, Ajello S, Beneduce A, Baldetti L, Vilca LM, Cappelletti A, Scandroglio AM, Azzalini L.

Letter Regarding Article, "The Evolving Landscape of Impella Use in the United States Among Patients Undergoing Percutaneous Coronary Intervention With Mechanical Circulatory Support

Circulation. 2020 Aug 11;142(6):e74-e75

Chieffo A, Gramegna M, Pappalardo F.

Strategies of left ventricular unloading during VA-ECMO support: a network meta-analysis

Int J Cardiol. 2020 Aug 1;312:16-21.

Baldetti L, Gramegna M, Beneduce A, Melillo F, Moroni F, Calvo F, Melisurgo G, Ajello S, Fominskiy E, Pappalardo F, Scandroglio AM.

Refractory Angina: From Pathophysiology to New Therapeutic Nonpharmacological Technologies

JACC Cardiovasc Interv. 2020 Jan 13;13(1):1-19.

Gallone G, Baldetti L, Tzanis G, Gramegna M, Latib A, Colombo A, Henry TD, Giannini F.

Pulmonary hypertension and right ventricular involvement in hospitalised patients with COVID-19

Heart. 2020 Sep;106(17):1324-1331.

Pagnesi M, Baldetti L, Beneduce A, Calvo F, Gramegna M, Pazzanese V, Ingallina G, Napolano A, Finazzi R, Ruggeri A, Ajello S, Melisurgo G, Camici PG, Scarpellini P, Tresoldi M, Landoni G, Ciceri F, Scandroglio AM, Agricola E, Cappelletti AM.

Acute myocarditis presenting as a reverse Tako-Tsubo syndrome in a patient with SARS-CoV-2 respiratory infection

Eur Heart J. 2020 May 14;41(19):1861-1862.

Sala S, Peretto G, Gramegna M, Palmisano A, Villatore A, Vignale D, De Cobelli F, Tresoldi M, Cappelletti AM, Basso C, Godino C, Esposito A.

Plaque rupture and intact fibrous cap assessed by optical coherence tomography portend different outcomes in patients with acute coronary syndrome

Eur Heart J. 2015 Jun 7;36(22):1377-84.

Niccoli G, Montone RA, Di Vito L, Gramegna M, Refaat H, Scalone G, Leone AM, Trani C, Burzotta F, Porto I, Aurigemma C, Prati F, Crea F.

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