Emanuela Setola

Biographie

Dr. Emanuela Setola is the Head of the Cardio-Metabolic Unit and Clinical Trials at the Metabolic Medicine Unit of IRCCS Ospedale San Raffaele, directed by Professor Emanuele Bosi.

After graduating in Medicine and Surgery in 1999 from the University of Milan, she specialized in Endocrinology and Metabolic Diseases in 2005. Subsequently, in 2011, she obtained her Ph.D. in Clinical and Experimental Nutrition, also from the University of Milan.

Dr. Setola's clinical and outpatient activities primarily focus on diabetes, dyslipidemias, and endocrinology. She is the point of contact for diabetes consultations for the Cardiovascular Department at Ospedale San Raffaele.

She engages in daily clinical research on the management of diabetes mellitus and its cardio-renal complications. Dr. Setola is the principal investigator of several sponsored clinical studies concerning the treatment of diabetes mellitus, dyslipidemias, cardiovascular diseases, and renal insufficiency. She has authored and co-authored 50 publications in scientific journals in her field.

Éducation

University of Milan
Degree in Medicine and Surgery - 1999

University of Milan
Specialization in Endocrinology and Metabolic Diseases - 2005

University of Milan
PhD in Experimental and Clinical Nutrition - 2011

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Publications

Dernières publications

Smoking is associated with impaired glucose regulation and a decrease in insulin sensitivity and the disposition index in first-degree relatives of type 2 diabetes subjects independently of the presence of metabolic syndrome
Acta Diabetol. 2014;51(5):793-799.
Piatti P, Setola E, Galluccio E, Costa S, Fontana B, Stuccillo M, Crippa V, Cappelletti A, Margonato A, Bosi E, Monti LD.
A novel truncated form of eNOS associates with altered vascular function
Cardiovasc Res. 2014 Mar 1;101(3):492-502
Galluccio E, Cassina L, Russo I, Gelmini F, Setola E, Rampoldi L, Citterio L, Rossodivita A, Kamami M, Colombo A, Alfieri O, Carini M, Bosi E, Trovati M, Piatti P, Monti LD, Casari G.
Strategie per migliorare il profilo delle nuove insuline: aspetti molecolari e possibili benefici clinici
Medico e Paziente 2014
Setola E, Monti LD., Crippa VG, Piatti PM.
La Terapia insulinica nel diabete mellito di tipo 2: per quali pazienti e con quali modalità
Medico e Paziente, 2013
Setola E, Monti LD, PIATTI PM
A novel truncated form of eNOS associates with altered vascular function
Cardiovasc Res. 2014; 101:492-502.
Galluccio E, Cassina L, Russo I, Gelmini F, Setola E, Rampoldi L, Citterio L, Rossodivita A, Kamami M, Colombo A, Alfieri O, Carini M, Bosi E, Trovati M, Piatti P, Monti LD, Casari G.
L-arginine enriched biscuits improve endothelial function and glucose metabolism: a pilot study in healthy subjects and a cross-over study in subjects with impaired glucose tolerance and metabolic syndrome
Metabolism. 2013 Feb;62(2):255-64.
Monti LD, Casiraghi MC, SETOLA E, Galluccio E, Pagani MA, Quaglia L, Bosi E, Piatti P
Effect of normalization of fasting glucose by intensified insulin therapy and influence of eNOS polymorphisms on the incidence of restenosis after peripheral angioplasty in patients with type 2 diabetes: a randomized, open-label clinical trial
Acta Diabetol. 2013 Jun;50(3):373-82
Piatti PM, Marone E, Mantero M, Setola E, Galluccio E, Lucotti P, Shehaj E, Villa V, Perticone F, Venturini M, Palini A, Airoldi F, Faglia E, Del Maschio A, Colombo A, Chiesa R, Bosi E, Monti LD
Aerobic and resistance training effects compared to aerobic training alone in obese type 2 diabetic patients on diet treatment
Diabetes Res Clin Pract. 2011 Dec;94(3):395-403.
Lucotti P, Monti LD, Setola E, Galluccio E, Gatti R, Bosi E, Piatti P.
Effects of chronic elevation of atrial natriuretic peptide and free fatty acid levels in the induction of type 2 diabetes mellitus and insulin resistance in patients with mitral valve disease
Nutr Metab Cardiovasc Dis. 2012 Jan 22 :58-65.
Monti LD, Lucotti PC, SETOLA E, Rossidivita A, Pala MG, Galluccio E, Lacanna G, Castiglioni A, Cannoletta M, Meloni C, Zavaroni I, Bosi E, Alfieri O, Piatti PM.
Fasting hyperinsulinemia associates with increased sub-clinical inflammation in first-degree relatives normal glucose tolerant women independently of the metabolic syndrome
Diabetes Metab Res Rev. 2009 Diabetes Metab Res. Rev 2009 25:639-46.
Setola E, Monti LD, Lucotti P, Galluccio E, Oldani M, Bosi E, Piatti P.
Oral L-arginine supplementation improves endothelial function and ameliorates insulin sensitivity and inflammation in cardiopathic nondiabetic patients after an aortocoronary bypass
Metabolism. 2009 Sep;58(9):1270-6.
Lucotti P, Monti L, Setola E, La Canna G, Castiglioni A, Rossodivita A, Pala MG, Formica F, Paolini G, Catapano AL, Bosi E, Alfieri O, Piatti P
Incretin-based therapies in type 2 diabetes: a review of clinical results
Diabetes Research and Clinical Practice 2008 82, suppl 2:S102-107.
Bosi E, Lucotti P, Setola E, Monti L, Piatti P.
Beneficial role of L-arginine in cardiac matrix remodelling in insulin resistant rats
Eur J Clin Invest 2008 38:849-856.
Monti LD, Galluccio E, Lucotti P, Setola E, Costa S, Fontana B, OldaniM; Merante D; Di Blasi P; BOSI E, PIATTI PM.
Increased insulin-stimulated endothelin-1 release is a distinct vascular phenotype distinguishing Cushing's disease from metabolic syndrome
Clin Endocrinol (Oxf). 2007;66:586-92.
Setola E, Losa M, Lanzi R, Lucotti P, Monti LD, Castrignano’ T, Galluccio E, Giovanelli M, Piatti P
Insulin resistance and endothelial function are improved after folate and vitamin B12 therapy in patients with the metabolic syndrome: relationship between homocysteine levels and hyperinsulinemia
European Journal Endocrinology 2004; 151:483-489.
Setola E, Monti LD, Galluccio E, Palloshi A, Fragasso G, Paroni R, Magni F, Sandoli EP, Lucotti P, Costa S, Fermo I, Galli-Kienle M, Origgi A, Margonato A and Piatti PM

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