Massimo Bernardi

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Specialty:

Hematology and Bone Marrow Transplantation in Adults Hematology Oncology

Profession:

Hematologist

Location:

Department of Hematology and Bone Marrow Transplantation @ Ospedale San Raffaele

Languages:

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Biography

Dr. Massimo Bernardi is Head of the Functional Department of Hematology and of the Disease Unit – Acute Leukemia and Myelodysplasia in the Department of Hematology and Bone Marrow Transplantation of the IRCCS Ospedale San Raffaele under the supervision of Professor Fabio Ciceri.

In 1988 he graduated in Medicine and Surgery at the University of Milan, where he specialized in respiratory diseases in 1994 and in Hematology in 2000.

From the point of view of clinical activity, Dr. Bernardi provides assistance to patients suffering from hematological diseases in the Department of Hematology. In particular, he deals with patients suffering from acute myeloid leukemia and myelodysplasia, with a complete diagnosis and determination of treatment options.

He collaborates and participates in both spontaneous and multicenter studies related to the diagnosis and treatment of acute leukemia and myelodysplasia, especially in elderly patients. It is devoted to the determination of prognostic indicators for the analysis of decision-making in the diagnosis, as well as in the prevention and treatment of relapses of the disease.

Currently, there are 112 publications in national and international journals (Hirsch Index 32) and in the chapters of university textbooks for medical students and surgeons.

He is a member of various societies and working groups, national and international: Francesco Lo Coco Acute Myeloid Leukemia Academy, European Haematology Association (EHA), Chronic Leukemia Working Party of EBMT (European Blood and Marrow Transplantation group), Acute Leukemia Working Party of EBMT, commissions on acute leukemias of the Lombard Hematology Network (REL), the REL Myelodysplasia Commission, the MDS Foundation (Myelodysplastic Syndromes), the GITMO Group for the Study of Myelodysplastic Syndromes (Italian Bone Marrow Transplantation Group).

Education

University of Milan
Degree of Doctor of Medicine and Surgery - 1988

University of Milan
Specialization in Diseases of the Respiratory System - 1994

University of Milan
Specialization in Hematology - 2000

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Publications

Latest publications

Real-World Validation of Molecular International Prognostic Scoring System for Myelodysplastic Syndromes

J Clin Oncol. 2023;41(15):2827-2842. doi: 10.1200/JCO.22.01784

Sauta E, Robin M, Bersanelli M, Travaglino E, Meggendorfer M, Zhao L, Caballero Berrocal JC, Sala C, Maggioni G, Bernardi M, Di Grazia C, Vago L, Rivoli G, Borin L, D'Amico S, Tentori CA, Ubezio M, Campagna A, Russo A, Mannina D, Lanino L, Chiusolo P, Giaccone L, Voso MT, Riva M, Oliva EN, Zampini M, Riva E, Nibourel O, Bicchieri M, Bolli N, Rambaldi A, Passamonti F, Savevski V, Santoro A, Germing U, Kordasti S, Santini V, Diez-Campelo M, Sanz G, Sole F, Kern W, Platzbecker U, Ades L, Fenaux P, Haferlach T, Castellani G, Della Porta MG

Longitudinal single-cell profiling of chemotherapy response in acute myeloid leukemia

Nat Commun. 2023;14(1):1285. doi: 10.1038/s41467-023-36969-0

Naldini MM, Casirati G, Barcella M, Rancoita PMV, Cosentino A, Caserta C, Pavesi F, Zonari E, Desantis G, Gilioli D, Carrabba MG, Vago L, Bernardi M, Di Micco R, Di Serio C, Merelli I, Volpin M, Montini E, Ciceri F, Gentner B

AVALON: The Italian cohort study on real-life efficacy of hypomethylating agents plus venetoclax in newly diagnosed or relapsed/refractory patients with acute myeloid leukemia

Cancer. 2023;129(7):992-1004. doi: 10.1002/cncr.34608. Epub 2023 Jan 24. PMID: 36692409

Todisco E, Papayannidis C, Fracchiolla N, Petracci E, Zingaretti C, Vetro C, Martelli MP, Zappasodi P, Di Renzo N, Gallo S, Audisio E, Griguolo D, Cerchione C, Selleri C, Mattei D, Bernardi M, Fumagalli M, Rizzuto G, Facchini L, Basilico CM, Manfra I, Borlenghi E, Cairoli R, Salutari P, Gottardi M, Molteni A, Martini V, Lunghi M, Fianchi L, Cilloni D, Lanza F, Abruzzese E, Cascavilla N, Rivellini F, Ferrara F, Maurillo L, Nanni J, Romano A, Cardinali V, Gigli F, Roncoroni E, Federico V, Marconi G, Volpi R, Sciumè M, Tarella C, Rossi G, Martinelli G; AVALON Cooperative Group

Imaging biomarkers of leukaemic choroidopathy

Acta Ophthalmol. 2023;101(5):553-559. doi: 10.1111/aos.15637

Menean M, Apuzzo A, Mastaglio S, Bernardi M, Ciceri F, Modorati G, Miserocchi E, Bandello F, Cicinelli MV

Levofloxacin prophylaxis vs no prophylaxis in neutropenic patients within an endemic country for carbapenem-resistant GNB

Blood Adv. 2023;7(9):1621-1634. doi: 10.1182/bloodadvances.2022008226

Clerici D, Galli L, Greco R, Lugli AP, Erbella F, Ripa M, Tassan Din C, Nitti R, Giglio F, Mastaglio S, Lorentino F, Xue E, Farina F, Liberatore C, Poli A, Carletti S, Lupo Stanghellini MT, Carrabba MG, Assanelli AA, Ruggeri A, Bernardi M, Corti C, Peccatori J, Mancini N, Scarpellini P, Ciceri F, Castagna A, Oltolini C

A sex-informed approach to improve the personalised decision making process in myelodysplastic syndromes: a multicentre, observational cohort study

Lancet Haematol 2022, Lancet Haematol. 2023;10(2): e117-e128.doi:10.1016/S2352-3026(22)00323-4

GenoMed4All consortium authors: Maggioni G, Bersanelli M, Travaglino E, Piérola A, Annika Kasprzak A, Sangerman Montserrat A, Sauta E, Sala C, Matteuzzi T, Meggendorfer M, Gnocchi M, Zhao L, Tentori CA , Nachtkamp K, Dall’Olio D, Mosca E, Ubezio M, Campagna A, Russo A, Rivoli G, Bernardi M, Borin L, Voso MT, Riva M, Oliva EN, Zampini M, Riva E, Saba E, D’Amico S, Lanino L, Tinterri B, Re F, Bicchieri M, Giordano L, Angelotti G, Morandini P, Kubasch AS, Passamonti F, Rambaldi A, Savevski V, Santoro A, Van de Loosdrecht AA, Brogi A, Santini V, Kordasti S, Sanz G, Sole F, Gattermann N, Kern W, Platzbecker U, Ades L, Fenaux P, Haferlach T, Castellani G, Germing U, Diez-Campelo M, Della Porta MG

Cytomegalovirus-specific T cells restricted for shared and donor human leukocyte antigens differentially impact on Cytomegalovirus reactivation risk after allogeneic hematopoietic stem cell transplantation

Haematologica. 2023 Jun 1;108(6):1530-1543. doi: 10.3324/haematol.2022.280685

Tassi E, Noviello M, De Simone P, Lupo-Stanghellini MT, Doglio M, Serio F, Abbati D, Beretta V, Valtolina V, Oliveira G, Racca S, Campodonico E, Ruggiero E, Clerici D, Giglio F, Lorentino F, Dvir R, Xue E, Farina F, Oltolini C, Manfredi F, Vago L, Corti C, Bernardi M, Clementi M, Brix L, Ciceri F, Peccatori J, Greco R, Bonini C

Prevalence and Prognostic Role of IDH Mutations in Acute Myeloid Leukemia: Results of the GIMEMA AML1516 Protocol.

Cancers, 2022;14(12):3012. doi: 10.3390/cancers14123012

Messina M, Piciocchi A, Ottone T, Paolini S, Papayannidis C, Lessi F, Fracchiolla NS, Forghieri F, Candoni A, Mengarelli A, Martelli MP, Venditti A, Carella AM, Albano F, Mancini V, Bernardi M, Arena A, Sargentini V, Sciumè M, Pastore D, Todisco E, Roti G, Siragusa S, Ladetto M, Pravato S, De Bellis E, Simonetti G, Marconi G, Cerchione C, Fazi P, Vignetti M, Amadori S, Martinelli G, Voso MT

MRD in venetoclax-based treatment for AML: does it really matter?

Front Oncol 2022, Jul 18;12:890871. doi: 10.3389/fonc.2022.890871

Bernardi M, Ferrara F, Carrabba MG, Mastaglio S, Lorentino F, Vago L, Ciceri F

Retinal Microvascular Changes in Patients with Acute Leukemia

Retina. 2022;42(9):1762-1771. doi: 10.1097/IAE.0000000000003504

Cicinelli MV, Mastaglio S, Menean M, Marchese A, Miserocchi E, Modorati G, Bernardi M, Ciceri F, Bandello F

Allogeneic hematopoietic stem cell transplantation in patients older than 65 years with acute myeloid leukemia and myelodysplastic syndrome: a 15-year experience

Bone Marrow Transplant. 2022; 57:678–680; https://doi.org/10.1038/s41409-022-01600-1

Piemontese S, Lazzari L, Ruggeri A, Marcatti M, Lupo Stanghellini MT, Giglio F, Greco R, Lorentino F, Clerici D, Assanelli A, Farina F, Mastaglio S, Xue E, Marktel S, Vago L, Gentner B, Secco C, Corti C, Carrabba MG, Bernardi M, Peccatori J, Ciceri F

Drug treatment options for acute promyelocytic leukemia

Expert Opin Pharmacother. 2022;23(1):117-127. doi: 10.1080/14656566.2021.1961744

Ferrara F, Molica M, Bernardi M

Human T cells engineered with a leukemia lipid-specific TCR enables donor-unrestricted recognition of CD1c-expressing leukemia

Nature Communications 2021; 12(1):4844. doi: 10.1038/s41467-021-25223-0.

Consonni M, Garavaglia C, Grilli A, de Lalla C, Mancino A, Mori L, De Libero G, Montagna D, Casucci M, Serafini M, Bonini C, Häussinger D, Ciceri F, Bernardi M, Mastaglio S, Bicciato S, Dellabona P, Casorati G

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