Claudio Doglioni - 预约 - GSD - 意大利医院集团

个人简介

Claudio Doglioni教授是米兰IRCCS圣拉斐尔科学研究医院病理解剖科主任，同时也是圣拉斐尔生命健康大学病理解剖学正教授。

他从费拉拉大学医学院毕业，之后在帕尔马大学专修病理解剖学和实验室技术。1986年，获得费拉拉大学肿瘤学专业学位。1991年，担任伦敦大学学院病理学系访问学者。1999年，在西雅图华盛顿大学病理学系任访问学者。

Doglioni教授专攻胰腺、肺和乳房相关疾病的诊断和研究，每年成功诊治4000余名患者。此外，他在免疫组化领域拥有丰富经验。他是首位查明Calretinin作为间皮瘤标记物、CDX2蛋白作为结肠肿瘤标记物以及p63作为乳腺病理问题中肌上皮细胞标记物背后机制的专家。其研究方向为免疫组化部分和分子诊断部分。Doglioni教授成功证明了抗生素治疗在MALT型胃部淋巴瘤的治疗中对根除幽门螺旋杆菌感染的有效性，做出了卓越的医学贡献。

他主要关注肿瘤学中诊断和预后分子标记物的确定、参与肿瘤形成的基因分子变化的鉴别、感染因子在MALT淋巴瘤（黏膜淋巴组织）中的致病作用研究以及各种免疫组化方法的应用。

他以作者身份在国际期刊（如The American Journal of Pathology、Genes & Development、Laboratory Investigation、Anticancer Research、Blood、Annals of Oncology、Clinical Cancer Research和Lancet）上发表了420篇文章（影响因子为1.802,578，Scopus数据库中的H指数为75）。Doglioni教授是Advanced in Anatomic Patholofy and Pathologica期刊的编委会成员，也是国际病理学会、美国科学促进会、意大利病理解剖学会的成员，同时还是意大利免疫组化组（GYM）的联合创始人。

教育背景

费拉拉大学
医学学位 - 1978年

帕尔马大学
病理解剖学和实验室技术专业学位 - 1981年

费拉拉大学
肿瘤学专业学位 - 1986年

出版物

他以作者身份在国内外期刊（如The American Journal of Pathology、Genes & Development、Laboratory Investigation、Anticancer Research、Blood、Annals of Oncology、Clinical Cancer Research和Lancet）上发表了420篇文章（影响因子为1.802,578，Scopus数据库中的H指数为75）。

最新出版物

Four-class tumor staging for early diagnosis and monitoring of murine pancreatic cancer using magnetic resonance and ultrasound.

CARCINOGENESIS, ISSN: 0143-3334, doi: 10.1093/carcin/bgy094

Dugnani, Erica, Pasquale, Valentina, Marra, Paolo, Liberati, Daniela, Canu, Tamara, Perani, Laura, De Sanctis, Francesco, Ugel, Stefano, Invernizzi, Francesca, Citro, Antonio, Venturini, Massimo, Doglioni, Claudio, Esposito, Antonio, Piemonti, Lorenzo (2018).

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Combined circulating tumor DNA and protein biomarker-based liquid biopsy for the earlier detection of pancreatic cancers.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, vol. 114, p. 10202-10207. (2017).

Cohen JD, Javed AA, Thoburn C., Wong F., Tie J., Gibbs P., Schmidt CM, Yip-Schneider MT, Allen PJ, Schattner M., Brand RE, Singhi AD, Petersen GM, Hong SM, Kim SC, Falconi M., Doglioni C., Weiss MJ, Ahuja N., He J., Makary MA, Maitra A., Hanash SM, Dal Molin M., Wang Y., Li L., Ptak J., Dobbyn L., Schaefer J., Silliman N., Popoli M., Goggins MG, Hruban RH, Wolfgang CL, Klein AP, Tomasetti C., Papa

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How to prepare, handle, read, and improve EUS-FNA and fine-needle biopsy for solid pancreatic lesions: The pathologist's role.

ENDOSCOPIC ULTRASOUND, vol. 6, p. S95-S98. (2017).

Biermann K., Escario MDL, Hébert-Magee S., Rindi G., Doglioni C.

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PD-L1 Expression and CD8 T-cell Infiltrate are Associated with Clinical Progression in Patients with Node-positive Prostate Cancer.

EUROPEAN UROLOGY FOCUS, ISSN: 2405-4569, doi: 10.1016/j.euf.2017.05.013. (2017).

Petitprez Florent, Fossati Nicola, Vano Yann, Freschi Massimo, Becht Etienne, Luciano Roberta, Calderaro Julien, Guedet Tiffany, Lacroix Laetitia, Rancoita Paola M.V., Montorsi Francesco, Fridman Wolf Herman, Sautes-Fridman Catherine, Briganti Alberto, Doglioni Claudio, Bellone Matteo.

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PML promotes metastasis of triple-negative breast cancer through transcriptional regulation of HIF1A target genes.

JCI INSIGHT, vol. 2, ISSN: 2379-3708, doi: 10.1172/jci.insight.87380. (2017).

Ponente M., Campanini L., Cuttano R., Piunti A., Delledonne GA, Coltella N., Valsecchi R., Villa A., Cavallaro U., Pattini L., Doglioni C., Bernardi R.

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TFH-derived dopamine accelerates productive synapses in germinal centres.

NATURE, vol. 547, p. 318-323. (2017).

Papa, Ilenia, Saliba, David, Ponzoni, Maurilio, Bustamante, Sonia, Canete, Pablo F., Gonzalez-Figueroa, Paula, McNamara, Hayley A., Valvo, Salvatore, Grimbaldeston, Michele, Sweet, Rebecca A., Vohra, Harpreet, Cockburn, Ian A., Meyer-Hermann, Michael, Dustin, Michael L., Doglioni, Claudio, Vinuesa, Carola G.

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Selecting patients for resection after primary chemotherapy for non-metastatic pancreatic adenocarcinoma.

ANNALS OF ONCOLOGY, vol. 28, p. 2786-2792, ISSN: 0923-7534, doi: 10.1093/annonc/mdx495 (2017).

Reni, M., Zanon S., Balzano G., Nobile S., Pircher CC, Chiaravalli M., Passoni P., Arcidiacono PG, Nicoletti R., Crippa SS, Slim N., Doglioni C., Falconi M., Gianni L.

Gastroenteric neuroendocrine neoplasms classification: comparison of prognostic models.

CANCER, vol. 119, p. 36-44, ISSN: 0008-543X, doi: 10.1002/cncr.27716 (2013).

Dolcetta Capuzzo A., Villa V., Albarello L., Franchi GM, Gemma M., Scavini M., Di Palo S., Orsenigo E., Bos, Emanuele, Doglioni, Claudio, Manzoni MF.

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Germinal center dysregulation by histone methyltransferase EZH2 promotes lymphomagenesis.

THE JOURNAL OF CLINICAL INVESTIGATION, vol. 123, p. 5009-5022 (2013).

Caganova M., Carrisi C., Varano G., Mainoldi F., Zanardi F., Germain PL, George L., Alberghini F, Ferrarini L, Talukder AK, PONZONI , MAURILIO, Testa G, Nojima T, DOGLIONI , CLAUDIO, Kitamura D, Toellner KM, Su IH, Casola S.

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Nodular lymphocyte predominant Hodgkin lymphoma with non-invasive or early invasive growth pattern suggests an early step of the disease with a highly favorable outcome.

AMERICAN JOURNAL OF HEMATOLOGY, vol. 88, p. 161-162

Carbone A., Spina M., Gloghini A., Ponzoni, Maurilio, Doglioni, Claudio, Tirelli U. (2013).

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