Francesca Lorentino

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专科:

血液学与骨髓移植科血液科移植医学

职业:

血液科医生

医疗机构:

血液科与骨髓移植科 @ 圣拉斐尔科学研究医院

语言:

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个人简介

Francesca Lorentino医生是IRCCS圣拉斐尔科学研究医院血液病和骨髓移植科的血液病专家兼移植专家，在Fabio Ciceri教授的指导下开展工作。

2011年毕业于圣拉斐尔生命健康大学医学院，2017年获得同一所大学的血液学专业学位。2020年11月起，先后获得米兰比可卡大学公共健康、生物统计学和流行病学博士学位。Lorentino医生多次参与海外实习，曾与巴黎的EBMT急性白血病工作组合作，担任接受同种异体骨髓移植患者的多中心登记研究的主要研究员。

临床上，Lorentino医生主要负责接受过同种异体骨髓移植、基因治疗和细胞治疗（如嵌合抗原T细胞受体[CAR-T细胞]）的恶性血液病患者。

作为研究员，Lorentino医生目前参与了以下工作组的临床试验：意大利骨髓移植工作组（GITMO）、急性白血病工作组以及细胞治疗和免疫生物学工作组DELL'EBMT。

她以作者或共同作者的身份在意大利国内外学术期刊上发表了25篇文章，也参与了多个书籍章节的编写。她经常参加意大利国内外的行业会议。

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出版物

最新出版物

Microbiome Markers are Early Predictors of Acute GvHD in Allogeneic Hematopoietic Stem Cell Transplant recipients

Blood. 2020 Nov 10:blood.2020007158. doi: 10.1182/blood.2020007158.

Greco R, Nitti R, Mancini N, Pasciuta R, Lorentino F, Lupo-Stanghellini MT, Barbanti MC, Clementi N, Giglio F, Clerici D, Marktel S, Assanelli AA, Carrabba MG, Bernardi M, Corti C, Peccatori J, Clementi M, Ciceri F.

Donor Lymphocyte Infusions After Allogeneic Stem Cell Transplantation in Acute Leukemia: A Survey From the Gruppo Italiano Trapianto Midollo Osseo (GITMO)

Front Oncol. 2020 Oct 15;10:572918. doi: 10.3389/fonc.2020.572918. eCollection 2020.

Patriarca F, Sperotto A, Lorentino F, Oldani E, Mammoliti S, Isola M, Picardi A, Arcese W, Saporiti G, Sorasio R, Mordini N, Cavattoni I, Musso M, Borghero C, Mic C, Fanin R, Bruno B, Ciceri F, Bonifazi F.

Post-transplantation cyclophosphamide GvHD prophylaxis after hematopoietic stem cell transplantation from 9/10 or 10/10 HLA-matched unrelated donors for acute leukemia

Leukemia. 2020 May 14. doi:10.1038/s41375-020-0863-4. Online ahead of print.

Lorentino F, Labopin M, Ciceri F, Vago L, Fleischhauer K, Afanasyev B, Kr ger N, Cornelissen JJ, Lovira M, Meijer E, Vitek A, Elmaagacli A, Blaise D, Ruggeri A, Chabannon C, Nagler A, Mohty M; Acute Leukemia Working Party (ALWP) and Cellular Therapy and Immunobiology Working Party (CTIWP) of the European Society for Blood and Marrow Transplantation (EBMT).

Mechanisms of Leukemia Immune Evasion and Their Role in Relapse After Haploidentical Hematopoietic Cell Transplantation

Front Immunol. 2020 Feb 25;11:147. doi: 10.3389/fimmu.2020.00147. eCollection 2020.

Rovatti PE†, Gambacorta V†, Lorentino F†, Ciceri F, Vago L. †= equal contribution.

Infections after Allogenic Transplant with Post-Transplant Cyclophosphamide: Impact of Donor HLA Matching

Biol Blood Marrow Transplant. 2020 Jun;26(6):1179-1188. doi: 10.1016/j.bbmt.2020.01.013. Epub 2020 Jan 28.

Oltolini C, Greco R, Galli L, Clerici D, Lorentino F, Xue E, Lupo Stanghellini MT, Giglio F, Uhr L, Ripa M, Scarpellini P, Bernardi M, Corti C, Peccatori J, Castagna A, Ciceri F.

Interleukin-6 as Biomarker for Acute GvHD and Survival After Allogeneic Transplant With Posttransplant Cyclophosphamide

Front. Immunol., 01 October 2019 |

Raffaella Greco†, Francesca Lorentino†, Rosamaria Nitti, Maria Teresa Lupo Stanghellini, Fabio Giglio, Daniela Clerici, Elisabetta Xue, Lorenzo Lazzari, Simona Piemontese, Sara Mastaglio, Andrea Assanelli, Sarah Marktel, Consuelo Corti, Massimo Bernardi, Fabio Ciceri††and Jacopo Peccatori†. †= equal contribution.

Comparative evaluation of biological human leukocyte antigen DPB1 mismatch models for survival and graft-versus-host disease prediction after unrelated donor hematopoietic cell transplantation

Haematologica. 2020 Apr;105(4):e186-e189. doi: 10.3324/haematol.2019.225177. Epub 2019 Aug 30.

Lorentino F, Sacchi N, Oldani E, Miotti V, Picardi A, Gallina AM, Crivello P, Bernasconi P, Saccardi R, Farina L, Benedetti F, Cerno M, Grassi A, Bruno B, Patriarca F, Ciceri F, Fleischhauer K, Vago L, Bonifazi F.

Comparable outcomes of haploidentical, 10/10 and 9/10 unrelated donor transplantation in adverse karyotype AML in first complete remission

Am J Hematol. 2018 Oct;93(10):1236-1244. doi: 10.1002/ajh.25231. Epub 2018 Sep 3.

Lorentino F, Labopin M, Bernardi M, Ciceri F, Soci G, Cornelissen JJ, Esteve J, Ruggeri A, Volin L, Yacoub-Agha I, Craddock C, Passweg J, Blaise D, Gedde-Dahl T, Poiani M, Fegueux N, Mohty M, Nagler A; Acute Leukemia Working Party of the European Society for Blood and Marrow Transplantation.

Killer cell immunoglobulin-like receptor ligand mismatching and outcome after haploidentical transplantation with post-transplant cyclophosphamide

Leukemia. 2019 Jan;33(1):230-239. doi: 10.1038/s41375-018-0170-5. Epub 2018 Jun 15.

Shimoni A, Labopin M, Lorentino F, Van Lint MT, Koc Y, Gülbas Z, Tischer J, Bruno B, Blaise D, Pioltelli P, Afanasyev B, Ciceri F, Mohty M, Nagler A.

The impact of HLA matching on outcomes of unmanipulated haploidentical HSCT is modulated by GVHD prophylaxis

Blood Advances 2017 1:669-680; doi:

Francesca Lorentino, Myriam Labopin, Katharina Fleischhauer, Fabio Ciceri, Carlheinz R. Mueller, Annalisa Ruggeri, Avichai Shimoni, Martin Bornh user, Andrea Bacigalupo, Zafer Gülbas, Yener Koc, William Arcese, Benedetto Bruno, Johanna Tischer, Didier Blaise, Giuseppe Messina, Dietrich W. Beelen, Arnon Nagler and Mohamad Mohty.

扩展阅读

NK cell recovery after haploidentical HSCT with post-transplant cyclophosphamide: dynamics and clinical implications

Blood 2017 :blood-2017-05-780668; doi:

Antonio Russo, Giacomo Oliveira, Sofia Berglund, Raffaella Greco, Valentina Gambacorta, Nicoletta Cieri, Cristina Toffalori, Laura Zito, Francesca Lorentino, Simona Piemontese, Mara Morelli, Fabio Giglio, Andrea Assanelli, Maria Teresa Lupo Stanghellini, Chiara Bonini, Jacopo Peccatori, Fabio Ciceri,Leo Luznik and Luca Vago.

Post-transplant cyclophosphamide and Sirolimus after Haploidentical HSCT Using a Treosulfan-based myeloablative conditioning and PBSC

Blood. 2016 Sep 15;128(11):1528-31.

Nicoletta Cieri MD, Raffaella Greco, Lara Crucitti, Mara Morelli, Fabio Giglio, Giorgia Levati, Andrea Assanelli, Matteo Carrabba, Laura Bellio, Raffaella Milani, Francesca Lorentino, Maria Teresa Lupo Stanghellini, Tiago De Freitas, Sarah Marktel, Massimo Bernardi, Consuelo Corti, Luca Vago, Chiara Bonini, Fabio Ciceri and Jacopo Peccatori. BBMT, 015 Aug;21(8):1506-14. Posttransplantation cycloph

Control of infectious mortality due to carbapenemase-producing Klebsiella pneumoniae in hematopoietic stem cell transplantation

Bone Marrow Transplant. 2016 Sep 26.

Forcina A, Baldan R, Marasco V, Cichero P, Bondanza A, Noviello M, Piemontese S, Soliman C, Greco R, Lorentino F, Giglio F, Messina C, Carrabba M, Bernardi M, Peccatori J, Moro M, Biancardi A, Nizzero P, Scarpellini P, Cirillo DM, Mancini N, Corti C, Clementi M, Ciceri F.

Post-transplant cyclophosphamide versus antithymocyte-globulin as graft versus host disease prophylaxis in haploidentical transplant

Haematologica. 2016 Oct 6.

Ruggeri A, Sun Y, Labopin M, Bacigalupo A, Lorentino F, Arcese W, Santarone S, Gülbas Z, Blaise D, Messina G, Ghavamzadeh A, Malard F, Bruno B, Diez-Martin JL, Koc Y, Ciceri F, Mohty M, Nagler A.

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