Stefano Cascinu

个人简介

Stefano Cascinu教授是米兰圣拉斐尔科学研究医院肿瘤内科主任。肿瘤内科包括肿瘤科、门诊和肿瘤科日间医院。Cascinu教授还在圣拉斐尔生命健康大学担任肿瘤内科教授。

1985年,Cascinu教授毕业于安科纳大学医学院;1988年,在该大学获得肿瘤学专业学位;2002年,在博洛尼亚大学获得肿瘤放疗专业学位;还在美国纽约的爱因斯坦医学院完成了实习。

在临床上,Cascinu教授主要关注胃肠道肿瘤的治疗,尤其是对食管、胃、结肠、胰腺和胆道肿瘤的治疗。

在胃癌和胰腺癌的治疗方面,Cascinu教授做出了宝贵的贡献。

Cascinu教授的研究活动集中于胃肠道肿瘤的生物学特性分析和创新疗法的开发。

Cascinu教授撰写或合著了525篇学术期刊论文和书籍章节,H指数为56。此外,Cascinu教授经常参加这些领域的意大利国内外大会。

教育背景

安科纳大学
医学学位 - 1985年

安科纳大学
肿瘤学专业学位 - 1988年

博洛尼亚大学
癌症放射治疗专业学位 - 2002年

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出版物

最新出版物

Breast ultrasonography (BU) in the screening protocol for women at hereditary-familial risk of breast cancer: has the time come to rethink the role of BU according to different risk categories?
Int J Cancer. 2019 Mar 1;144
Cortesi L, Canossi B, Battista R, Pecchi A, Drago A, Dal Molin C, Toss A, De Matteis E, Marchi I, Torricelli P, Cascinu S.
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GISCAD investigators Treatment sequence with either irinotecan/cetuximab followed by FOLFOX-4 or the reverse strategy in metastatic colorectal cancer patients progressing after first-line FOLFIRI/bevacizumab: An Italian Group for the Study of Gastrointestinal Cancer phase III, randomised trial comparing two sequences of therapy in colorectal metastatic patients.
Eur J Cancer. 2017 Sep;83:106-115.
Cascinu S, Rosati G, Nasti G, Lonardi S, Zaniboni A, Marchetti P, Leone F, Bilancia D, Iaffaioli RV, Zagonel V, Giordano M, Corsi DC, Ferraú F, Labianca R, Ronzoni M, Scartozzi M, Galli F
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Randomized trial of low-dose morphine versus weak opioids in moderate cancer pain.
Journal of Clinical Oncology 2016; 34: 436–42
Bandieri E, Romero M, Ripamonti CI, et al.
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Addressing the challenges of pancreatic cancer: Future directions for improving outcomes.
Pancreatology 2015; 15: 8–12
Hidalgo M, Cascinu S, Kleeff J, et al
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Panitumumab versus cetuximab in patients with chemotherapy-refractory wild-type KRAS exon 2 metastatic colorectal cancer (ASPECCT): A randomised, multicentre, open-label, noninferiority phase 3 study.
The Lancet Oncology 2014; 15:
Price TJ, Peeters M, Kim TW, et al
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Cetuximab plus irinotecan, fluorouracil, and leucovorin as first-line treatment for metastatic colorectal cancer: Updated analysis of overall survival according to tumor KRAS and BRAF mutation status.
Journal of Clinical Oncology 2011; 29: 2011–9
Van Cutsem E, Köhne C-H, Láng I, et al
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PTEN expression and KRAS mutations on primary tumors and metastases in the prediction of benefit from cetuximab plus irinotecan for patients with metastatic colorectal cancer
Journal of Clinical Oncology 2009; 27: 2622–9
Loupakis F, Pollina L, Stasi I, et al.
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Cetuximab plus gemcitabine and cisplatin compared with gemcitabine and cisplatin alone in patients with advanced pancreatic cancer:a randomised, multicentre, phase II trial.
The Lancet Oncology 2008; 9: 39–44
Cascinu S, Berardi R, Labianca R, et al.
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Nuclear factorkB tumor expression predicts response and survival in irinotecan-refractory metastatic colorectal cancer treated with cetuximab-irinotecan therapy.
Journal of Clinical Oncology 2007; 25: 3930–5
Scartozzi M, Bearzi I, Pierantoni C, et al
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Pharmacogenetic profiling and clinical outcome of patients with advanced gastric cancer treated with palliative chemotherapy.
Journal of Clinical Oncology 2006; 24: 1883–91
Ruzzo A, Graziano F, Kawakami K, et al.
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Prognostic role of interleukin-1ß gene and interleukin-1 receptor antagonist gene polymorphisms in patients with advanced gastric cancer.
Journal of Clinical Oncology 2005; 23: 2339–45
Graziano F, Ruzzo A, Santini D, et al
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Epidermal growth factor receptor (EGFR) status in primary colorectal tumors does not correlate with EGFR expression in related metastatic sites: Implications for treatment with EGFR-targeted monoclonal antibodies.
Journal of Clinical Oncology 2004; 22: 4720–6
Scartozzi M, Bearzi I, Berardi R, Mandolesi A, Fabris G, Cascinu S.
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Association of CDH1 haplotypes with susceptibility to sporadic diffuse gastric cancer.
Oncogene 2002; 21: 8192–5
Humar B, Graziano F, Cascinu S, et al.
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Neuroprotective effect of reduced glutathione on cisplatin-based chemotherapy in advanced gastric cancer: A randomized double-blind placebo-controlled trial.
Journal of Clinical Oncology 1995; 13: 26–32
Cascinu S, Cordella L, Del Ferro E, Fronzoni M, Catalano G.
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Recombinant human erythropoietin treatment in cisplatinassociated anemia: A randomized, double-blind trial with placebo.
Journal of Clinical Oncology 1994; 12: 1058–62
Cascinu S, Fedeli A, Del Ferro E, Luzi Fedeli S, Catalano G.
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