Failure of implantation, recurrent pregnancy loss
What is it?
Implantation failure is defined as failure to achieve pregnancy after 3 or more embryo transfers with good quality embryos. Recurrent pregnancy loss is defined as the loss of more than 2 pregnancies at a gestational age of less than 10 weeks or even only 1 pregnancy at an ultrasound gestational age greater than or equal to 10 weeks.
Which are the symptoms?
- failure of 3 or more embryotransfers
- more than 2 abortions <10 weeks
- 1 abortion > 10 weeks ultrasound
How is it diagnosed?
When any of the conditions described above occur, a patient should have a screening of blood tests that may show pre-existing conditions that can cause miscarriages or implantation failures. Another examination that can be performed is diagnostic hysteroscopy to evaluate the uterine cavity and the possible presence of chronic endometritis.
How is it treated?
Based on the results of the prescribed examinations, therapies are prescribed to resolve the diagnosed pathological condition. If no deviations are found in tests, an empirical therapy can be prescribed to help to improve the chance of embryo implantation (both in case of spontaneous pregnancy and in case of IVF pregnancy).
Where do we treat it?
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