Giuseppe Magnani

Profession:
Neurologist
Languages:
FR
FR
IT
IT

Biography

Dr. Giuseppe Magnani is a neurologist at the Neurology Unit of IRCCS Ospedale San Raffaele, directed by Professor Massimo Filippi. He also serves as the Area Coordinator of the Memory Disorders Unit and the Cognitive Disorders and Dementias Center (CDCD, formerly UVA Center) within the Department of Neurology and Clinical Neurophysiology at the same hospital.

He is a contract professor of Neurogeriatrics at the School of Specialization in Neurology, Vita-Salute San Raffaele University, Milan.

Dr. Magnani graduated with honors in Medicine and Surgery from the University of Milan in 1986 and specialized in Neurology with honors at the same institution in 1991. From 1989 to 2000, he worked as a Medical Assistant at the Neurological Clinic IV at the University of Milan, IRCCS Ospedale San Raffaele. From 2000 to 2002, he was a First-Level Medical Director at the Neurological Clinic of Vita-Salute University. Between 2002 and 2008, he served as a Senior First-Level Medical Director in the Neurology and Neurophysiology Unit at the same hospital.

From 2000 to 2009, Dr. Magnani was the Head of the Memory Disorders Unit and the UVA Center in the Department of Neurology and Clinical Neurophysiology at IRCCS Ospedale San Raffaele. From 2009 to 2018, he was the Area Coordinator of the Memory Disorders Unit and UVA Center at INSPE, IRCCS Ospedale San Raffaele. Since 2019, he has been the Area Coordinator of the Memory Disorders Unit and the Head of the Cognitive Disorders and Dementias Center (CDCD, formerly UVA Center) within the Department of Neurology and Clinical Neurophysiology.

His clinical work focuses primarily on dementia-related diseases, particularly Alzheimer's disease, Lewy body dementia, frontotemporal dementia, and its variants. He has participated in numerous national and international pharmacological trials. Dr. Magnani provides clinical care in the Neurology ward, particularly in the Emergency Department and Neurology ward, handling neurological emergencies and conducting outpatient clinics, especially concerning Alzheimer's disease and other dementias.

He has extensive clinical experience in general neurology, with a particular emphasis on neurodegenerative diseases. He is also an expert electroencephalographer and was a member of the Brain Death Verification Commission for organ transplants at IRCCS Ospedale San Raffaele from 1991 to 2012.

Earlier in his career, he engaged in research in neurophysiology, focusing on evoked potentials and electroencephalography, including advanced methods such as high-resolution EEG and Event-Related Desynchronization applied to clinical settings. Since 2000, his research has centered on Alzheimer's disease and other dementias, particularly studying cerebrospinal fluid biomarkers for the early diagnosis of Alzheimer's disease.

Read moreRead less

Education

State University of Milan
Degree in Medicine and Surgery - 1986

State University of Milan
Specialization in Neurology - 1991

Do you need an appointment?

Contact us and we will take care of you.

Publications

Latest publications

Combining Cerebrospinal Fluid Biomarkers and Neuropsychological Assessment: A Simple and Cost-Effective Algorithm to Predict the Progression from Mild Cognitive Impairment to Alzheimer's Disease Dementia
J Alzheimers Dis. 2016 Oct 18;54(4):1495-1508. doi: 10.3233/JAD-160360. PMID: 27589522.
Mazzeo S, Santangelo R, Bernasconi MP, Cecchetti G, Fiorino A, Pinto P, Passerini G, Falautano M, Comi G, Magnani G.
Cerebrospinal fluid biomarkers can play a pivotal role in the diagnostic work up of primary progressive aphasia
J Alzheimers Dis. 2015;43(4):1429-40. doi: 10.3233/JAD-141122. PMID: 25201781.
Santangelo R, Coppi E, Ferrari L, Bernasconi MP, Pinto P, Passerini G, Comi G, Magnani G.
Cerebrospinal Fluid Amyloid-β 42, Total Tau and Phosphorylated Tau are Low in Patients with Normal Pressure Hydrocephalus: Analogies and Differences with Alzheimer's Disease
J Alzheimers Dis. 2017;60(1):183-200. doi: 10.3233/JAD-170186. PMID: 28826180.
Santangelo R, Cecchetti G, Bernasconi MP, Cardamone R, Barbieri A, Pinto P, Passerini G, Scomazzoni F, Comi G, Magnani G.
BIOMARKAPD Project. FDG-PET and CSF biomarker accuracy in prediction of conversion to different dementias in a large multicentre MCI cohort
Neuroimage Clin. 2018 Jan 28;18:167-177. doi: 10.1016/j.nicl.2018.01.019. PMID: 29387532; PMCID: PMC5790816.
Caminiti SP, Ballarini T, Sala A, Cerami C, Presotto L, Santangelo R, Fallanca F, Vanoli EG, Gianolli L, Iannaccone S, Magnani G, Perani D;
Sturge-Weber syndrome with an unusual onset in the sixth decade: a case report
Neurol Sci. 2012 Aug;33(4):949-50. doi: 10.1007/s10072-011-0822-y. Epub 2011 Oct 22. PMID: 22020422.
Ferrari L, Coppi E, Caso F, Santangelo R, Politi LS, Martinelli V, Comi G, Magnani G.
The CSF p-tau181/Aβ42 Ratio Offers a Good Accuracy "In Vivo" in the Differential Diagnosis of Alzheimer's Dementia
Curr Alzheimer Res. 2019;16(7):587-595. doi: 10.2174/1567205016666190725150836. PMID: 31345148.
Santangelo R, Dell'Edera A, Sala A, Cecchetti G, Masserini F, Caso F, Pinto P, Leocani L, Falautano M, Passerini G, Martinelli V, Comi G, Perani D, Magnani G.
Plasma neurofilament light chain levels and cognitive testing as predictors of fast progression in Alzheimer's disease
Eur J Neurol. 2021 Sep;28(9):2980-2988. doi: 10.1111/ene.14999. Epub 2021 Jul 23. PMID: 34176186.
Santangelo R, Agosta F, Masi F, Spinelli EG, Cecchetti G, Caso F, Mandelli A, Cardamone R, Barbieri A, Furlan R, Magnani G, Filippi M.
Cross-validation of biomarkers for the early differential diagnosis and prognosis of dementia in a clinical setting
7/s00259-015-3170-y. Epub 2015 Sep 4. Erratum in: Eur J Nucl Med Mol Imaging. 2016 Jan;43(1):202-3. PMID: 26341365.
Perani D, Cerami C, Caminiti SP, Santangelo R, Coppi E, Ferrari L, Pinto P, Passerini G, Falini A, Iannaccone S, Cappa SF, Comi G, Gianolli L, Magnani G.
Further evidence about the crucial role of CSF biomarkers in diagnosis of posterior cortical atrophy
Neurol Sci. 2014 May;35(5):785-7. doi: 10.1007/s10072-014-1644-5. Epub 2014 Feb 2. PMID: 24487699.
Coppi E, Ferrari L, Santangelo R, Caso F, Pinto P, Passerini G, Comi G,Magnani G.
Prevalence of amyloid-β pathology in distinct variants of primary progressive aphasia
Ann Neurol. 2018 Nov;84(5):729-740. doi: 10.1002/ana.25333. PMID: 30255971; PMCID: PMC6354051.
Bergeron D, Gorno-Tempini ML, Rabinovici GD, Santos-Santos MA, Seeley W, Miller BL, Pijnenburg Y, Keulen MA, Groot C, van Berckel BNM, van der Flier WM, Scheltens P, Rohrer JD, Warren JD, Schott JM, Fox NC, Sanchez-Valle R, Grau- Rivera O, Gelpi E, Seelaar H, Papma JM, van Swieten JC, Hodges JR, Leyton CE, Piguet O, Rogalski EJ, Mesulam MM, Koric L, Nora K, Pariente J, Dickerson B, Mackenzie IR, Hsiung GR, Belliard S, Irwin DJ, Wolk DA, Grossman M, Jones M,Harris J, Mann D, Snowden JS, Chrem-Mendez P, Calandri IL, Amengual AA, Miguet-Alfonsi C, Magnin E, Magnani G, Santangelo R, Deramecourt V, Pasquier F, Mattsson N, Nilsson C, Hansson O, Keith J, Masellis M, Black SE, Matías-Guiu JA, Cabrera-Martin MN, Paquet C, Dumurgier J, Teichmann M, Sarazin M, Bottlaender M, Dubois B, Rowe CC, Villemagne VL, Vandenberghe R, Granadillo E, Teng E, Mendez M, Meyer PT, Frings L, Lleó A, Blesa R, Fortea J, Seo SW, Diehl-Schmid J, Grimmer T, Frederiksen KS, Sánchez-Juan P, Chételat G, Jansen W, Bouchard RW, Laforce RJ, Visser PJ, Ossenkoppele R.
CSF p-tau/Aβ42 ratio and brain FDG-PET may reliably detect MCI "imminent" converters to AD
Eur J Nucl Med Mol Imaging. 2020 Dec;47(13):3152-3164. doi:10.1007/s00259-020-04853-4. Epub 2020 May 15. PMID: 32415550.
Santangelo R, Masserini F, Agosta F, Sala A, Caminiti SP, Cecchetti G, Caso F, Martinelli V, Pinto P, Passerini G, Perani D, Magnani G, Filippi M.
Brain metabolic signatures across the Alzheimer's disease spectrum
Eur J Nucl Med Mol Imaging. 2020 Feb;47(2):256-269. doi: 10.1007/s00259-019-04559-2. Epub 2019 Dec 7. PMID: 31811345.
Sala A, Caprioglio C, Santangelo R, Vanoli EG, Iannaccone S, Magnani G, Perani D.
Resting-state electroencephalographic biomarkers of Alzheimer's disease
Neuroimage Clin. 2021;31:102711. doi: 10.1016/j.nicl.2021.102711. Epub 2021 May 29. PMID: 34098525; PMCID: PMC8185302.
Cecchetti G, Agosta F, Basaia S, Cividini C, Cursi M, Santangelo R, Caso F, Minicucci F, Magnani G, Filippi M.
The brain metabolic signature of visual hallucinations in dementia with Lewy bodies
Cortex. 2018 Nov;108:13-24. doi: 0.1016/j.cortex.2018.06.014. Epub 2018 Jul 4. PMID: 30098477.
Iaccarino L, Sala A, Caminiti SP, Santangelo R, Iannaccone S, Magnani G, Perani D.
The combined effects of microglia activation and brain glucose hypometabolism in early-onset Alzheimer's disease
Alzheimers Res Ther. 2020 Apr 30;12(1):50. doi: 10.1186/s13195-020-00619-0. PMID: 32354345; PMCID: PMC7193377.reak
Tondo G, Iaccarino L, Caminiti SP, Presotto L, Santangelo R, Iannaccone S, Magnani G, Perani D.

Do you need an appointment?

Contact us and we will take care of you.