Roberta Messina

Profession:
Neurologist
Languages:
EN
EN
IT
IT

Biography

Dr. Roberta Messina is a neurologist specializing in Headaches and Facial Pain at the Neurology Unit of IRCCS Ospedale San Raffaele, directed by Prof. Massimo Filippi.

After graduating in Medicine and Surgery from Università Vita-Salute San Raffaele in 2011, with honors, she specialized in Neurology at the same university, obtaining her Neurologist title in 2018 (grade: 70/70 with honors).

During her specialization, she worked for 18 months at the Headache Centre of King's College London, where she deepened her knowledge and skills in the diagnosis and treatment of headaches and facial pain.

After completing her specialization, she embarked on a PhD in Experimental Neurology at Università Vita-Salute San Raffaele. During her PhD, she conducted extensive research on the use of advanced MRI techniques to understand the mechanisms underlying migraine attacks and cluster headache attacks. She contributed to several academic projects in collaboration with national and international researchers.

Her clinical work focuses primarily on the diagnosis and treatment of primary headaches, such as migraines, tension-type headaches, and cluster headaches, secondary headaches, and facial pain, including trigeminal neuralgia. She is involved in numerous clinical trials assessing the efficacy and safety of new therapies for migraine prevention.

She has had the opportunity to work at two major International Headache Centers, the Headache Centre of King's College London and the Danish Headache Centre in Copenhagen.

Her research aims to achieve a better understanding of the causes and pathogenic mechanisms involved in migraine and other forms of headaches using advanced MRI techniques.

Additionally, she focuses on studying preventive and acute therapies for migraines, with the goal of identifying the most effective and personalized treatments for patients.

She is the author of numerous articles published in indexed journals and some book chapters. She is a member of the Editorial Board of The Journal of Headache and Pain, a reviewer for various scientific journals, a member of the Educational Committee of the International Headache Society, and a member of the Scientific Committee of the Italian Neurological Association for Headache Research.

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Publications

Latest publications

Imaging the brain and vascular reactions to headache treatments: a systematic review
J Headache Pain. 2023 May 24;24(1):58.
Messina R, Christensen RH, Cetta I, Ashina M, Filippi M.
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Safety and tolerability of monoclonal antibodies targeting the CGRP pathway and gepants in migraine prevention: A systematic review and network meta-analysis.
Cephalalgia. 2023 Mar;43(3):3331024231152169.
Messina R, Huessler EM, Puledda F, Haghdoost F, Lebedeva ER, Diener HC.
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Biomarkers of Migraine and Cluster Headache: Differences and Similarities
Ann Neurol. 2023 Apr;93(4):729-742.
Messina R, Sudre CH, Wei DY, Filippi M, Ourselin S, Goadsby PJ.
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Functional MRI in migraine
Curr Opin Neurol. 2022 Jun 1;35(3):328-335.
Messina R, Gollion C, Christensen RH, Amin FM.
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Tracking the evolution of non-headache symptoms through the migraine attack
J Headache Pain. 2022 Nov 23;23(1):149.
Messina R, Cetta I, Colombo B, Filippi M.
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Italian Migraine Registry study group. Predictors of response to anti-CGRP monoclonal antibodies: a 24-week, multicenter, prospective study on 864 migraine patients
J Headache Pain. 2022 Nov 1;23(1):138. Link a Pubmed:
Barbanti P, Egeo G, Aurilia C, Altamura C, d'Onofrio F, Finocchi C, Albanese M, Aguggia M, Rao R, Zucco M, Frediani F, Filippi M, Messina R, Cevoli S, Carnevale A, Fiorentini G, Messina S, Bono F, Torelli P, Proietti S, Bonassi S, Vernieri F;
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Clinical correlates of hypothalamic functional changes in migraine patients
Cephalalgia. 2022 Apr;42(4-5):279-290.
Messina R, Rocca MA, Valsasina P, Misci P, Filippi M.
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Tension-type headache
Nat Rev Dis Primers. 2021 Mar 25;7(1):24.
Ashina S, Mitsikostas D, Lee MJ, Yamani N, Wang SJ, Messina R, Ashina H, Buse D, Pozo-Rosich P, Jensen R, Diener HC, Lipton R.
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Discontinuing monoclonal antibodies targeting CGRP pathway after one-year treatment: an observational longitudinal cohort study
J Headache Pain. 2021 Dec 18;22(1):154.
Vernieri F, Brunelli N, Messina R, Costa CM, Colombo B, Torelli P, Quintana S, Cevoli S, Favoni V, d'Onofrio F, Egeo G, Rao R, Filippi M, Barbanti P, Altamura C.
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Candesartan in migraine prevention: results from a retrospective real-world study
J Neurol. 2020 Nov;267(11):3243-3247.
Messina R, Lastarria Perez CP, Filippi M, Goadsby PJ.
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The chronic migraine brain: What have we learned from neuroimaging?
Front Neurol. 2020 Jan 9; 10:1356.
Filippi M and Messina R.
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Dysregulation of multisensory processing stands out from an earyl stage of migraine: a study in pediatric patients
J Neurol. 2020 Mar;267(3):760-769.
Messina R, Rocca MA, Colombo B, Valsasina P, Meani A, Falini A, Filippi M.
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Gray matter volume modifications in migraine: A cross-sectional and longitudinal study
Neurology. 2018 Jul 17;91(3):e280-e292.
Messina R, Rocca MA, Colombo B, Pagani E, Falini A, Goadsby PJ, Filippi M.
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CGRP - a target for acute therapy in migraine: Clinical data
Cephalalgia. 2019 Mar;39(3):420-427.
Messina R and Goadsby PJ.
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Cortical abnormalities in patients with migraine: a surface-based analysis
Radiology 2013; 268: 170-180.
Messina R, Rocca MA, Colombo B, Valsasina P, Horsfield MA, Copetti M, Falini A, Comi G, Filippi M.
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Do you need an appointment?

Contact us and we will take care of you.