Ubaldo Del Carro

Profession:
Neurologist
Languages:
IT
IT

Biography

Dr. Ubaldo Del Carro is a neurologist at the Neurology Unit of IRCCS Ospedale San Raffaele, led by Professor Massimo Filippi. He is also the Director of Intraoperative Neurophysiology and the coordinator of the Pelvic Unit.

After earning his medical degree, Dr. Del Carro specialized in Neurology at the University of Milan. He began his association with the Neurology division of Ospedale San Raffaele in 1982, initially as a student and resident, and later advanced to the role of Assistant Neurologist in clinical practice.

Dr. Del Carro has participated in several practical residential courses, including the Electromyographic and Clinical Neurophysiopathology Culture Course at the University of Ferrara (1987), the Electroencephalography and Epileptology Training Course in Gargnano (BS) at the University of Milan, and a Practical Course on Neuro-Urology in Maastricht (2000).

During his specialization, Dr. Del Carro focused on muscular diseases, collaborating with U.I.L.D.M. for epidemiological studies on dystrophic myopathies and their neurophysiological classification.

Since 2001, as Head of the Neurophysiology Service, he has been involved in the functional diagnostics of central and peripheral nervous system pathologies (EMG and Multimodal Evoked Potentials), becoming the Head of the SINC Training Center for the EMG and EP module.

He has also served as the coordinator of the SINC Pelvic Floor Neurophysiology Study Group and is currently the coordinator of the Pelvic Unit at IRCCS Ospedale San Raffaele.

In the area of movement disorders, Dr. Del Carro is responsible for the clinic that treats focal dystonias and spasticity with Botulinum Toxin. He is also responsible for the clinic that treats chronic migraine headaches with Botulinum Toxin. In 2021, he was appointed Director of Intraoperative Neurophysiology.

Dr. Del Carro's research activities focus on clinical studies related to peripheral nerve diseases and disorders affecting the pelvic floor. His experimental research centers on the application of neurophysiological techniques in animal models (primates and rodents) of genetic and acquired diseases, aiming to refine sensitive methods for characterizing pathophysiological mechanisms and validating tools to assess the effectiveness of new and innovative therapeutic approaches.

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Education

University of Milan
Degree in Medicine and Surgery - 1985

University of Milan
Specialization in Neurology - 1989

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Publications

Latest publications

Treatment with IFB-088 Improves Neuropathy in CMT1A and CMT1B Mice
Neurobiol.: 2022; 59(7): 4159-4178 - Article
Bai, Y; Treins, C; Volpi, VG; Scapin, C; Ferri, C; Mastrangelo, R; Touvier, T; Florio, F; Bianchi, F; Del Carro, U; Baas, FF; Wang, D; Miniou, P; Guedat, P; Shy, ME and D’Antonio, M Mol.
Integrated evaluation of a panel of neurochemical biomarkers to optimize diagnosis and prognosis in amyotrophic lateral sclerosis
Neurol.: 2022; 29(7): 1930-1939 - Article
Falzone, YM; Domi, T; Mandelli, A; Pozzi, L; Schito, P; Russo, T; Barbieri, A; Fazio, R; Volontè, MA; Magnani, G; Del Carro, U; Carrera, P; Malaspina, A; Agosta, F; Quattrini, A; Furlan, R; Filippi, M; Riva, N Eur. J.
Lentiviral haematopoietic stem-cell gene therapy for early-onset metachromatic leukodystrophy: long-term results from a non-randomised, open-label, phase 1/2 trial and expanded access
Lancet: 2022; 399(10322): 372-383 - Article
Fumagalli, F and Calbi, V; Natali Sora, MG; Sessa, M; Baldoli, C; Rancoita, PMV; Ciotti, F; Sarzana, M; Fraschini, M; Zambon, AA; Acquati, S; Redaelli, D; Attanasio, V; Miglietta, S; De Mattia, F; Barzaghi, F; Ferrua, F; Migliavacca, M; Tucci, F; Gallo, V; Del Carro, U; Canale, S; Spiga, I; Lorioli, L; Recupero, S; Fratini, ES; Morena, F; Silvani, P; Calvi, MR; Facchini, M; Locatelli, S; Corti, A; Zancan, S; Antonioli, G; Farinelli, G; Gabaldo, M; Garcia-Segovia, J; Schwab, LC; Downey, GF; Filippi, M; Cicalese, MP; Martino, S; Di Serio, C; Ciceri, F; Bernardo, ME; Naldini, L; Biffi, A and Aiuti, A
ADAM17 Regulates p75NTR-Mediated Fibrinolysis and Nerve Remyelination
Neurosci: 2022; 42(12): 2433-2447 - Article
Pellegatta, M; Canevazzi, P; Forese, MG; Podini, P; Valenzano, S; Del Carro, U; Quattrini, A; Taveggia, C J
Surgical and Radiologic Prognostic Factors in Intramedullary Spinal Cord Lesions
World Neurosurg.: 2021; 150: e550-e560 – Article
Mortini, P; Morselli, C; Spina, A; Bailo, M; Del Carro, U; Boari, N
Two factor-based reprogramming of rodent and human fibroblasts into Schwann cells
Nat. Commun.: 2017; 8: 14088 - Article
Mazzara, PG; Massimino, L; Pellegatta, M; Ronchi, G; Ricca, A; Iannielli, A; Giannelli, SG; Cursi, M; Cancellieri, C; Sessa, A; Del Carro, U; Quattrini, A; Geuna, S; Gritti, A; Taveggia, C; Broccoli, V
Refractory chronic migraine: is drug withdrawal necessary before starting a therapy with onabotulinum toxin type A?
Neurol. Sci.: 2016; 37(10): 1701-1706 - Article
Butera, C; Colombo, B; Bianchi, F; Cursi, M; Messina, R; Amadio, S; Guerriero, R; Comi, G; Del Carro, U
Diagnostic tools for assessment of urinary dysfunction in MS patients without urinary disturbances
Neurol. Sci.: 2016; 37(3): 437-442 – Article
Ghezzi, A; Mutta, E; Bianchi, F; Bonavita, S; Buttari, F; Caramma, A; Cavarretta, R; Centonze, D; Coghe, GC; Coniglio, G; Del Carro, U; Ferrò, MT; Marrosu, MG; Patti, F; Rovaris, M; Sparaco, M; Simone, I; Tortorella, C; Bergamaschi, R
Lentiviral haemopoietic stem-cell gene therapy in early-onset metachromatic leukodystrophy: an ad-hoc analysis of a non-randomised, open-label, phase 1/2 trial
Lancet: 2016; 388(10043): 476-487 - Article
Sessa, M and Lorioli, L; Fumagalli, F; Acquati, S; Redaelli, D; Baldoli, C; Canale, S; Lopez, ID; Morena, F; Calabria, A; Fiori, R; Silvani, P; Rancoita, PMV; Gabaldo, M; Benedicenti, F; Antonioli, G; Assanelli, A; Cicalese, MP; Del Carro, U; Natali Sora, MG; Martino, S; Quattrini, A; Montini, E; Di Serio, C; Ciceri, F; Roncarolo, MG; Aiuti, A; Naldini, L; Biffi, A
Sensory tricks and brain excitability in cervical dystonia: A transcranial magnetic stimulation study
Mov. Disord.: 2014; 29(9): 1185-1188 – Article
Amadio, S; Houdayer, E; Bianchi, F; Tesfaghebriel Tekle, H; Urban, IP; Butera, C; Guerriero, R; Cursi, M; Leocani, L; Comi, G; Del Carro, U
Lentiviral Hematopoietic Stem Cell Gene Therapy Benefits Metachromatic Leukodystrophy
Science: 2013; 341(6148): 1233158 - Article
Biffi, A and Montini, E; Lorioli, L; Cesani, M; Fumagalli, F; Plati, T; Baldoli, C; Martino, S; Calabria, A; Canale, S; Benedicenti, F; Vallanti, G; Biasco, L; Leo, S; Kabbara, N; Zanetti, G; Rizzo, WB; Mehta, NA; Cicalese, MP; Casiraghi, M; Boelens, JJ; Del Carro, U; Dow, DJ; Schmidt, M; Assanelli, A; Neduva, V; Di Serio, C; Stupka, E; Gardner, J; von Kalle, C; Bordignon, C; Ciceri, F; Rovelli, A; Roncarolo, MG; Aiuti, A; Sessa, M; Naldini, L
Evaluation of polyneuropathy markers in type 1 diabetic kidney transplant patients and effects of islet transplantation: neurophysiological and skin biopsy longitudinal analysis
Diabetes Care: 2007; 30(12): 3063-3069 - Article
Del Carro, U; Fiorina, P; Amadio, S; De Toni Franceschini, L; Petrelli, A; Menini, S; Martinelli-Boneschi, F; Ferrari, S; Pugliese, G; Maffi, P; Comi, G; Secchi, A
Injection of adult neurospheres induces recovery in a chronic model of multiple sclerosis
Nature:2003; 422(6933):688-694 - Article
Pluchino, S; Quattrini, A; Brambilla, E; Gritti, A; Salani, G; Dina, G; Galli, R; DelCarro, U; Amadio, S; Bergami, A; Furlan, R; Comi, G; Vescovi, AL; Martino, G
Motor evoked potentials in a mouse model of chronic multiple sclerosis
Muscle Nerve:2006; 33(2): 265 - 273 - Article
Amadio, S; Pluchino, S; Brini, E; Morana, P; Guerriero, R; Martinelli-Boneschi, F; Comi, G; Zaratin, P; Muzio, V; Del Carro, U

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