Alessandro Larcher

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Specialty:

Urology Adult Urology Oncology Genitourinary Oncology

Location:

Department of Urology I @ Ospedale San Raffaele

Languages:

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Biography

Dr. Alessandro Larcher is a urologist in the Department of Urology of the Clinical Research Institute Ospedale San Raffaele, headed by Professor Francesco Montorsi.

He received a diploma in Medicine and Surgery from the Vita-Salute San Raffaele University in Milan in 2011. In 2014, he completed a scientific internship in the field of oncological urology in the Department of cancer diagnostics and analysis of medical examination results at the Hospital Center at the University of Montreal in Canada. In 2017, he specialized in urology and then became the Scientific Director of the ORSI Academy robot-assisted surgery training center in Melle, Belgium. In 2018, he completed his clinical and surgical practice in the field of robot-assisted surgery in the Department of Urology at the Onze Lieve Vrouw Ziekenhuis Hospital in Aalst, Belgium. Since 2019, he has been the Chairman of the Young Academic Urologist Working Group on Robot-assisted surgery of the European Society of Urology.

With regard to clinical activities, Dr. Larcher conducts examinations as a specialist and performs surgical interventions for major diseases of the male genitourinary system. He provides assistance to patients with tumors of the kidneys, prostate, bladder, ureter, testicles or penis. He also deals with the treatment of prostate hypertrophy, urolithiasis, urethral stenosis, pyeloureteral segment stenosis, varicocele, hydrocele, phimosis or infections of the urogenital tract.

During his internship in the Department of Urology of the Onze-Lieve-Vrouw Ziekenhuis Hospital in Aalst, Belgium, he studied in depth the use of robot-assisted surgery in the main types of major urological interventions such as radical and partial nephrectomy, radical prostatectomy, pelvic and retroperitoneal lymphadenectomy, radical cyst nephroureterectomy, pyeloplasty and ureteral reimplantation. Also, as the first surgeon and first assistant, he participated in live surgery or broadcast surgical online events.

As for research activities, Dr. Larcher has been conducting clinical and translational research at URI - Institute of Urological Research since 2010, focusing on kidney tumors with a detailed study of the diagnosis of the disease and its treatment using robotic-assisted surgery, reducing complications associated with surgical intervention, treatments that are alternatives to surgery, such as ablation or active surveillance, and surgical treatment in cases of metastases.

He is the author and co-author of over 170 original scientific articles published in leading international journals, including the Lancet and European Urology, the most prestigious journal in the field of urology. His Hirsch index is 26. He is a member of the Italian, European and American societies of urology and regularly participates as a speaker and moderator in national and international industry congresses. Since 2019, he has been an Assistant Editor at European Urology magazine. He has conducted research describing the first training program on robot-assisted renal tumor surgery, awarded by the Milan College of Physicians with La Fucina del Futuro Award in 2019 and by the Italian Society of Urology with Hans Marberger Award in 2020.

Publications

Latest publications

Individualised Indications for Cytoreductive Nephrectomy: Which Criteria Define the Optimal Candidates?

Eur Urol Oncol. 2019 Jul;2(4):365-378. doi: 10.1016/j.euo.2019.04.007. Epub 2019 May 18.

Larcher A, Wallis CJD, Bex A, Blute ML, Ficarra V, Mejean A, Karam JA, Van Poppel H, Pal SK.

Is Robot- assisted Surgery Contraindicated in the Case of Partial Nephrectomy for Complex Tumours or Relevant Comorbidities? A Comparative Analysis of Morbidity, Renal Function, and Oncologic Outcomes.

Eur Urol Oncol. 2018 May;1(1):61-68. doi: 10.1016/j.euo.2018.01.001. Epub 2018 May 15.

2: Larcher A, Capitanio U, De Naeyer G, Fossati N, D'Hondt F, Muttin F, De Groote R, Guazzoni G, Salonia A, Briganti A, Montorsi F, Mottrie A.

ERUS Educational Working Group and the Young Academic Urologist Working Group on Robot-assisted Surgery. The ERUS Curriculum for Robot-assisted Partial Nephrectomy: Structure Definition and Pilot Clinical Validation.

Eur Urol. 2019 Jun;75(6):1023-1031. doi: 10.1016/j.eururo.2019.02.031. Epub 2019 Apr 9.

Larcher A, De Naeyer G, Turri F, Dell'Oglio P, Capitanio U, Collins JW, Wiklund P, Van Der Poel H, Montorsi F, Mottrie A;

Virtual Reality Validation of the ERUS Simulation-based Training Programmes: Results from a High-volume Training Centre for Robot-assisted Surgery.

Eur Urol. 2019 May;75(5):885-887. doi: 10.1016/j.eururo.2019.02.008. Epub 2019 Feb 28.

Larcher A, Turri F, Bianchi L, Dell'Oglio P, Collins J, Capitanio U, Montorsi F, Mottrie A.

Robot-assisted versus open cystectomy in the RAZOR trial

Lancet 2019 Feb 16;393(10172):645. doi: 10.1016/S0140-6736(18)33006-X. Epub 2019 Feb 14.

Larcher A, Gandaglia G, Wiklund P, Mottrie A, Briganti A, Montorsi F; European Association of Urology Robotic Urology Section.

The Learning Curve for Robot-assisted Partial Nephrectomy: Impact of Surgical Experience on Perioperative Outcomes.

Eur Urol. 2019 Feb;75(2):253-256. doi: 10.1016/j.eururo.2018.08.042. Epub 2018 Sep 19.

Larcher A, Muttin F, Peyronnet B, De Naeyer G, Khene ZE, Dell'Oglio P, Ferreiro C, Schatteman P, Capitanio U, D'Hondt F, Montorsi F, Bensalah K, Mottrie A.

When to Perform Preoperative Bone Scintigraphy for Kidney Cancer Staging: Indications for Preoperative Bone Scintigraphy

Urology. 2017 Dec;110:114-120. doi: 10.1016/j.urology.2017.08.043. Epub 2017 Sep 7.

7: Larcher A, Muttin F, Fossati N, Dell'Oglio P, Di Trapani E, Stabile A, Ripa F, Trevisani F, Carenzi C, Picchio M, Briganti A, Salonia A, Mottrie A, Bertini R, Montorsi F, Capitanio U.

Prediction of Competing Mortality for Decision-making Between Surgery or Observation in Elderly Patients With T1 Kidney Cancer

Urology. 2017 Apr;102:130-137. doi: 10.1016/j.urology.2016.08.069. Epub 2016 Nov 21.

Larcher A, Trudeau V, Dell'Oglio P, Tian Z, Boehm K, Fossati N, Capitanio U, Briganti A, Montorsi F, Karakiewicz P.

When to perform preoperative chest computed tomography for renal cancer staging

BJU Int. 2017 Oct;120(4):490-496. doi: 10.1111/bju.13670. Epub 2016 Nov 2.

Larcher A, Dell'Oglio P, Fossati N, Nini A, Muttin F, Suardi N, De Cobelli F, Salonia A, Briganti A, Zhang X, Montorsi F, Bertini R, Capitanio U.

Elective Nephron Sparing Surgery Decreases Other Cause Mortality Relative to Radical Nephrectomy Only in Specific Subgroups of Patients with Renal Cell Carcinoma

J Urol. 2016 Oct;196(4):1008-13. doi: 10.1016/j.juro.2016.04.093. Epub 2016 May 25.

Larcher A, Capitanio U, Terrone C, Volpe A, De Angelis P, Dehó F, Fossati N, Dell'Oglio P, Antonelli A, Furlan M, Simeone C, Serni S, Carini M, Minervini A, Fiori C, Porpiglia F, Briganti A, Montorsi F, Bertini R.

Population-based assessment of cancer-specific mortality after local tumour ablation or observation for kidney cancer: a competing risks analysis

BJU Int. 2016 Oct;118(4):541-6. doi: 10.1111/bju.13326. Epub 2015 Oct 16.

Larcher A, Trudeau V, Sun M, Boehm K, Meskawi M, Tian Z, Fossati N, Dell'Oglio P, Capitanio U, Briganti A, Shariat SF, Montorsi F, Karakiewicz PI.

Prediction of Complications Following Partial Nephrectomy: Implications for Ablative Techniques Candidates

Eur Urol. 2016 Apr;69(4):676-682. doi:10.1016/j.eururo.2015.07.003. Epub 2015 Jul 21.

Larcher A, Fossati N, Tian Z, Boehm K, Meskawi M, Valdivieso R, Trudeau V, Dell'Oglio P, Buffi N, Montorsi F, Guazzoni G, Sun M, Karakiewicz PI.

Comparison of renal function detriments after local tumor ablation or partial nephrectomy for renal cell carcinoma

World J Urol. 2016 Mar;34(3):383-9. doi: 10.1007/s00345-015-1606-4. Epub 2015 Jun 6.

Larcher A, Meskawi M, Valdivieso R, Boehm K, Trudeau V, Tian Z, Fossati N, Dell'Oglio P, Lughezzani G, Buffi N, Sun M, Karakiewicz P.

Long-term oncologic outcomes of laparoscopic renal cryoablation as primary treatment for small renal masses

Urol Oncol. 2015 Jan;33(1):22.e1-22.e9. doi: 10.1016/j.urolonc.2014.09.003. Epub 2014 Oct 7.

Larcher A, Fossati N, Mistretta F, Lughezzani G, Lista G, Dell'Oglio P, Abrate A, Sun M, Karakiewicz P, Suardi N, Lazzeri M, Montorsi F, Guazzoni G, Buffi N.

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