Elisabetta Lapenna

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Specialty:

Cardiac Surgery Cardiovascular Diseases Arrhythmology and Electrophysiology

Profession:

Heart surgeon

Location:

Department of Cardiac Surgery @ Ospedale San Raffaele

Languages:

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Biography

Elisabetta Lapenna is the head of the Functional Department of Surgical Treatment of Cardiac Arrhythmias of the Department of Cardiac Surgery of the IRCCS Ospedale San Raffaele in Milan under the supervision of Professor Alessandro Castiglioni.

She graduated from the Faculty of Medicine and Surgery in 1995 with high marks at the Catholic University of the Sacred Heart in Rome and was awarded the Agostino Gemelli Prize of the 36th edition as the holder of the highest degree in Medicine / Curriculum Studiorum (1989 -1995). In 2001, she specialized in cardiac surgery at the same university. During her studies, she completed internships abroad at the European Homotransplant Bank in Brussels, the University Hospital Center in Nantes, St George's Hospital and Royal Brompton-Harefield Hospital in London.

Dr. Lapenna has performed more than 4,000 cardiac surgeries as a first and second surgeon, as well as using minimally invasive and thoracoscopic methods. In particular, in addition to mitral and aortic valve surgery, ascending aorta, hypertrophic cardiomyopathy and CABG, her interest is in heart failure surgery by implantation of ventricular support systems (L-VAD) and surgical treatment of atrial fibrillation using thoracoscopic procedures. With the arrhythmia treatment team of the department, she performed numerous procedures of hybrid endo-epicardial ablation of ventricular tachyarrhythmias through left mini-thoracotomy in collaboration with electrophysiologists.

Dr. Lapenna is an adjunct professor of the scientific sector MED/23 - Cardiac Surgery - within the framework of the Master's degree course in Medicine and Surgery at the University of Vita-Salute San Raffaele and at the School of Specialization of Cardiac Surgery of the same university.

She also taught a Master's degree in Engineering and Surgery for engineers at the Polytechnic University of Milan.

As a researcher, Dr. Lapenna has participated as a supervisor or co-investigator in numerous clinical trials characterized by collaboration at the national and international levels. He is the author and co-author of more than 100 publications in industry scientific journals and numerous chapters in books. His current Hirsch index is 18 (Scopus author ID: 56113466100).

Has a patent for a device for percutaneous treatment of tricuspid valvular insufficiency.

Permanent participant of national and international industry congresses.

Education

Catholic University of the Sacred Heart - Policlinico Gemelli, Rome
Degree of Doctor of Medicine and Surgery - 1995

Catholic University of the Sacred Heart - Policlinico Gemelli, Rome
Specialization in cardiac surgery - 2001

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Publications

Latest publications

Long-term outcomes of stand-alone Maze IV for persistent/long-standing persistent atrial fibrillation

Ann Thorac Surg. 2019 Jul 17

Lapenna E, De Bonis M, Giambuzzi I, Del Forno B, Ruggeri S, Cireddu M, Gulletta S, Castiglioni A, Alfieri O, Della Bella P, Benussi S.

Durability at 19 Years of Quadrangular Resection With Annular Plication for Mitral Regurgitation.

Ann Thorac Surg. 2018 Sep;106(3):735-741.

Lapenna E, Del Forno B, Amore L, Ruggeri S, Iaci G, Schiavi D, Belluschi I, Bargagna M, Alfieri O, De Bonis M.

Second crossclamping after mitral valve repair for degenerative disease in contemporary practice.

Eur J Cardiothorac Surg. 2018 Jul 1;54(1):91-97.

De Bonis M, Lapenna E, Giambuzzi I, Meneghin R, Affronti G, Pappalardo F, Castiglioni A, Trumello C, Buzzatti N, Giacomini A, Raimondi Lucchetti M, Alfieri O

Minimally invasive or conventional edge-to-edge repair for severe mitral regurgitation due to bileaflet prolapse in Barlow's disease: does the surgical approach have an impact on the long-term results?

Eur J Cardiothorac Surg. 2017 Apr 11. doi: 10.1093/ejcts/ezx032

De Bonis M, Lapenna E, Del Forno B, Di Sanzo S, Giacomini A, Schiavi D, Vicentini L, Latib A, Pozzoli A, Pappalardo F, La Canna G, Alfieri O.

Long-term results (up to 14 years) of the clover technique for the treatment of complex tricuspid valve regurgitation.

Eur J Cardiothorac Surg. 2017 Feb 23.

De Bonis M, Lapenna E, Di Sanzo S, Del Forno B, Pappalardo F, Castiglioni A, Vicentini L, Pozzoli A, Giambuzzi I, Latib A, Schiavi D, La Canna G, Alfieri O.

Mid-term outcomes of concomitant surgical ablation of atrial fibrillation in patients undergoing cardiac surgery for hypertrophic cardiomyopathy

Eur J Cardiothorac Surg. 2017 Jun 1;51(6):1112-1118

Lapenna E, Pozzoli A, De Bonis M, La Canna G, Nisi T, Nascimbene S, Vicentini L, Di Sanzo S, Del Forno B, Schiavi D, Alfieri O.

Long-term results of mitral repair in patients with severe left ventricular dysfunction and secondary mitral regurgitation: does the technique matter?

Eur J Cardiothorac Surg. 2016 Apr 28. pii: ezw139

De Bonis M, Lapenna E, Barili F, Nisi T, Calabrese M, Pappalardo F, La Canna G, Pozzoli A, Buzzatti N, Giacomini A, Alati E, Alfieri O.

Optimal results immediately after MitraClip therapy or surgical edge-to-edge repair for functional mitral regurgitation: are they really stable at 4 years?

Eur J Cardiothorac Surg. 2016 Mar 23

De Bonis M, Lapenna E, Buzzatti N, La Canna G, Denti P, Pappalardo F, Schiavi D, Pozzoli A, Cioni M, Di Giannuario G, Alfieri O.

Very long-term results (up to 17 years) with the double-orifice mitral valve repair combined with ring annuloplasty for degenerative mitral regurgitation.

JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY, vol. 144, p. 1019-1026, ISSN: 0022-5223, doi:10.1016/j.jtcvs.2012.07.034

De Bonis M, Lapenna E, Lorusso R, Buzzati N, Gelsomino S, Taramasso M, Vizzardi E, Alfieri O (2012).

Long-term results (≤18 years) of the edge-to-edge mitral valve repair without annuloplasty in degenerative mitral regurgitation: implications for the percutaneous approach.

Circulation. 2014 Sep 9;130(11 Suppl 1):S19-24.

De Bonis M, Lapenna E, Maisano F, Barili F, La Canna G, Buzzatti N, Pappalardo F, Calabrese M, Nisi T, Alfieri O.

Very long-term durability of the edge-to-edge repair for isolated anterior mitral leaflet prolapse: up to 21 years of clinical and echocardiographic results.

Thorac Cardiovasc Surg. 2014 Nov;148(5):2027- 32. doi: 10.1016/j.jtcvs.2014.03.041. Epub 2014 Mar 27.

De Bonis M, Lapenna E, Taramasso M, La Canna G, Buzzatti N, Pappalardo F, Alfieri O.

The clover technique for the treatment of complex tricuspid valve insufficiency: midterm clinical and echocardiographic results in 66 patients.

EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY, vol. 37, p. 1297-1303.

Lapenna E, De Bonis M, Verzini A, La Canna G, Ferrara D, Calabrese MC, Taramasso M, Alfieri O

Commissural closure for the treatment of commissural mitral valve prolapse or flail.

JOURNAL OF HEART VALVE DISEASE, vol.17, p. 261-266

Lapenna E, De Bonis M, Sorrentino F, La Canna G, Grimaldi A, Torracca L, Maisano F, Alfieri O

Spinal cord stimulation for patients with refractory angina and previous coronary surgery.

ANNALS OF THORACIC SURGERY, 2006 vol. 82, p. 1704-1708.

Lapenna E, Rapati D, Cardano P, De Bonis M, Lullo F, Zangrillo A, Alfieri O

Minimally invasive mitral valve repair in the context of Barlow's disease.

ANNALS OF THORACIC SURGERY, vol. 79, p. 1496-1499, ISSN: 0003-4975, doi: 10.1016/j.athoracsur.2004.10.032

Lapenna E, Torracca L, De Bonis M, La Canna G, Crescenzi G, Alfieri O

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