Massimo Filippi

Massimo Filippi
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专科:
神经内科 神经和功能康复科 康复科
职业:
神经科医生
医疗机构:
神经内科与神经康复科 @ 圣拉斐尔科学研究医院
语言:
EN
IT
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个人简介

Massimo Filippi教授1961年8月31日出生于意大利蒙萨，1986年获得医学学位，1990年获得神经病学专业学位，1994年获得神经生理学专业学位。

Filippi教授目前是意大利米兰圣拉斐尔生命健康大学神经病学和神经康复学系负责人、MS中心主任、神经生理学服务中心主任、IRCCS圣拉斐尔科学研究医院神经影像学研究科室主任、圣拉斐尔生命健康大学神经病学正教授，还是该校神经病学住院医师培训学院主任、理疗学士学位点负责人。

2006年和2008年，Filippi教授分别担任贝尔格莱德大学和德国杜塞尔多夫大学的客座教授。

他的研究活动始终专注于确定导致各种神经系统疾病中不可逆的身体残疾和认知障碍进行性积累的机制。Filippi教授是意大利国内外多个科学协会和委员会的成员，并在其中一些协会或委员会中担任过或正在履行重要职责。

Filippi教授在同行评审期刊上发表了1320多篇论文，参与了多个国际期刊的编辑工作；他是Journal of Neurology的主编，Human Brain Mapping、Radiology和Neurological Sciences的副主编，还是许多国际学术期刊编辑委员会的成员。Filippi教授还定期为神经病学和神经影像学领域的其他机构审稿，也是许多政府部门和私人基金会的审核人。Filippi教授经常受邀担任意大利国内外神经内科学术会议的发言人和/或主席。

2001年，Filippi教授因对多发性硬化研究的杰出贡献获得Rita Levi Montalcini奖；2015年，在第六十七届西班牙神经内科学会（SEN）大会上获得Distinguished Dr Luis Barraquer Ferré Lecture的荣誉。

教育背景

米兰大学
医学学位 - 1986年

米兰大学
神经内科专业学位 - 1990年

帕维亚大学
神经病理生理学专业学位 - 1994年

多媒体中心

Multiple sclerosis: what are the symptoms and available treatments?

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出版物

Filippi教授是许多国际学术期刊编辑委员会的成员，还为神经病学和神经影像学领域的其他机构审稿，包括政府机构和私人基金会。Filippi教授也是Journal of Neurology的主编，Radiology和Neurological Sciences的副主编。Filippi教授发表了超过1000篇同行评审科研论文，总H指数为116（Scopus），还参与了196篇书籍章节的编写。

最新出版物

Interferon beta-1a for brain tissue loss in patients at presentation with syndromes suggestive of multiple sclerosis: a randomised, double-blind, placebo-controlled trial.
Lancet 2004; 364: 1489-1496
Filippi M, Rovaris M, Inglese M, Barkhof F, De Stefano N, Smith S, Comi G, and the ETOMS Study Group.
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Effects of oral glatiramer acetate on clinical and MRI-monitored disease activity in patients with relapsing multiple sclerosis: a multicentre, double-blind, randomised, placebo-controlled study
Lancet Neurol 2006; 5: 213-220 [Epub ahead of print, 2006 January 20]
Filippi M, Wolinsky JS, Comi G and the CORAL Study Group
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Effect of laquinimod on MRI-monitored disease activity in patients with relapsing-remitting multiple sclerosis: a multicentre, randomised, double-blind, placebo-controlled phase IIb study
Lancet 2008; 371: 2085-2092
Comi G, Pulizzi A, Rovaris M, Abramsky O, Arbizu T, Boiko A, Gold R, Havrdova E, Komoly S, Selmaj KW, Sharrack B, Filippi M for the LAQ/5062 Study Group
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Effect of glatiramer acetate on conversion to clinically definite multiple sclerosis in patients with clinically isolated syndrome (PreCISe study): a randomised, double-blind, placebo-controlled trial.
Lancet 2009;374:1503-1511 [Epub ahead of print 7 October 2009; doi: 10.1016/S0140-6736(09)61259-9]
Comi G, Martinelli V, Rodegher M, Moiola L, Bajenaru O, Carra A, Elovaara I, Fazekas F, Hartung HP, Hillert J, King J, Komoly S, Lubetzki C, Montalban X, Myhr KM, Ravnborg M, Rieckmann P, Wynn D, Young C, Filippi M for the PreCISe study group
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Assessment of brain system dysfunction through MRI-based connectomics.
Lancet Neurol 2013; 12: 1189-1199 [Epub ahead of print 11 October 2013; doi: 10.1016/S1474-4422(13)70144-3]
Filippi M, van den Heuvel MP, Fornito A, He Y, Hulshoff Pol HE, Agosta F, Comi G, Rocca MA
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Progress towards a neuroimaging biomarker for amyotrophic lateral sclerosis.
Lancet Neurol 2015; 14: 786-788 [doi: 10.1016/S1474-4422(15)00134-9]
Filippi M, Agosta F, Grosskreutz J, Benatar M, Kassubek J, Verstraete E, Turner MR, on behalf of the Neuroimaging Society in ALS (NiSALS)
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MRI criteria for the diagnosis of multiple sclerosis: MAGNIMS consensus guidelines.
Lancet Neurol 2016; 15: 292-303 [doi: 10.1016/S1474-4422(15)00393-
Filippi M, Rocca MA, Ciccarelli O, De Stefano N, Evangelou N, Kappos L, Rovira A, Sastre-Garriga J, Tintorè M, Frederiksen JL, Gasperini C, Palace J, Reich DS, Banwell B, Montalban X, Barkhof F, on behalf of the MAGNIMS Study Group.
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Brain network connectivity differs in early-onset neurodegenerative dementia.
Neurology 2017; 89: 1764-1772 [epub ahead of print 27 September 2017; doi: 10.1212/WNL.0000000000004577]
Filippi M, Basaia S, Canu E, Imperiale F, Meani A, Caso F, Magnani G, Falautano M, Comi G, Falini A, Agosta F.
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Long-term disability progression in primary progressive multiple sclerosis: a 15 year study.
Brain 2017; 140: 2814-2819 [epub ahead of print 27 September 2017; doi: 10.1093/brain/awx250]
Rocca MA, Sormani MP, Rovaris M, Caputo D, Ghezzi A, Montanari E, Bertolotto A, Laroni A, Bergamaschi R, Martinelli V, Comi G, Filippi M.
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Brain structural and functional signatures of impulsive-compulsive behaviours in Parkinson's disease.
Mol Psychiatr 2018; 23: 459-466 [Epub ahead of print 7 March 2017; doi: 10.1038/mp.2017.18]
Imperiale F, Agosta F, Canu E, Markovic V, Inuggi A, Jecmenica-Lukic M, Tomic A, Copetti M, Basaia S, Kostic VS, Filippi M.
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Prediction of a multiple sclerosis diagnosis in patients with clinically isolated syndrome using the 2016 MAGNIMS and 2010 McDonald criteria: a retrospective study
Lancet Neurol 2018; 17: 133-142 [epub ahead of print 21 December 2017; doi: 10.1016/S1474-4422(17)30469-6]
Filippi M, Preziosa P, Meani A, Ciccarelli O, Mesaros S, Rovira A, Frederiksen J, Enzinger C, Barkhof F, Gasperini C, Brownlee W, Drulovic J, Montalban X, Cramer SP, Pichler A, Hagens M, Ruggieri S, Martinelli V, Miszkiel K, Tintorè M, Comi G, Dekker I, Uitdehaag B, Dujmovic-Basuroski I, Rocca MA
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Unraveling ALS due to SOD1 mutation through the combination of brain and cervical cord MRI.
Neurology 2018; 90: e707-e716 [epub ahead of print 24 January 2018; doi: 10.1212/WNL.0000000000005002]
Agosta F, Spinelli EG, Marjanovic IV, Stevic Z, Pagani E, Valsasina P, Salak-Djokic B, Jankovic M, Lavrnic D, Kostic VS, Filippi M.
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Association between pathological and MRI findings in multiple sclerosis: an update.
Lancet Neurol 2019; 18: 198-210 [doi: 10.1016/S1474-4422(18)30451-4]
Filippi M, Brück W, Chard D, Fazekas F, Geurts JJG, Enzinger C, Hametner S, Kuhlmann T, Preziosa P, Rovira A, Schmierer K, Stadelmann C, Rocca MA, for the Attendees of the Correlation between Pathological and MRI findings in MS workshop.
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Assessment of lesions on magnetic resonance imaging in multiple sclerosis: practical guidelines.
Brain 2019; 142: 1858-1975 [epub ahead of print 17 June 2019; doi: 10.1093/brain/awz144]
Filippi M, Preziosa P, Banwell BL, Barkhof F, Ciccarelli O, De Stefano N, Geurts JJG, Paul F, Reich DS, Toosy AT, Traboulsee A, Wattjes MP, Yousry TA, Gass A, Lubetzki C, Weinshenker BG, Rocca MA.
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Changes in functional and structural brain connectome along the Alzheimer’s disease continuum.
Mol Psychiatr 2019 (in press) [epub ahead of print 9 May 2018; doi: 10.1038/s41380-018-0067-8]
Filippi M, Basaia S, Canu E, Imperiale F, Magnani G, Falautano M, Comi G, Falini A, Agosta F.
扩展阅读
Assessment of brain system dysfunction through MRI-based connectomics.
Lancet Neurol 2013; 12: 1189-1199 [Epub ahead of print 11 October 2013; doi: 10.1016/S1474-4422(13)70144-3]
Filippi M, van den Heuvel MP, Fornito A, He Y, Hulshoff Pol HE, Agosta F, Comi G, Rocca MA
Progress towards a neuroimaging biomarker for amyotrophic lateral sclerosis.
Lancet Neurol 2015; 14: 786-788 [doi: 10.1016/S1474-4422(15)00134-9]
Filippi M, Agosta F, Grosskreutz J, Benatar M, Kassubek J, Verstraete E, Turner MR, on behalf of the Neuroimaging Society in ALS (NiSALS)
MRI criteria for the diagnosis of multiple sclerosis: MAGNIMS consensus guidelines.
Lancet Neurol 2016; 15: 292-303 [doi: 10.1016/S1474-4422(15)00393-
Filippi M, Rocca MA, Ciccarelli O, De Stefano N, Evangelou N, Kappos L, Rovira A, Sastre-Garriga J, Tintorè M, Frederiksen JL, Gasperini C, Palace J, Reich DS, Banwell B, Montalban X, Barkhof F, on behalf of the MAGNIMS Study Group.
Brain network connectivity differs in early-onset neurodegenerative dementia.
Neurology 2017; 89: 1764-1772 [epub ahead of print 27 September 2017; doi: 10.1212/WNL.0000000000004577]
Filippi M, Basaia S, Canu E, Imperiale F, Meani A, Caso F, Magnani G, Falautano M, Comi G, Falini A, Agosta F.
Prediction of a multiple sclerosis diagnosis in patients with clinically isolated syndrome using the 2016 MAGNIMS and 2010 McDonald criteria: a retrospective study
Lancet Neurol 2018; 17: 133-142 [epub ahead of print 21 December 2017; doi: 10.1016/S1474-4422(17)30469-6]
Filippi M, Preziosa P, Meani A, Ciccarelli O, Mesaros S, Rovira A, Frederiksen J, Enzinger C, Barkhof F, Gasperini C, Brownlee W, Drulovic J, Montalban X, Cramer SP, Pichler A, Hagens M, Ruggieri S, Martinelli V, Miszkiel K, Tintorè M, Comi G, Dekker I, Uitdehaag B, Dujmovic-Basuroski I, Rocca MA
Unraveling ALS due to SOD1 mutation through the combination of brain and cervical cord MRI.
Neurology 2018; 90: e707-e716 [epub ahead of print 24 January 2018; doi: 10.1212/WNL.0000000000005002]
Agosta F, Spinelli EG, Marjanovic IV, Stevic Z, Pagani E, Valsasina P, Salak-Djokic B, Jankovic M, Lavrnic D, Kostic VS, Filippi M.
Association between pathological and MRI findings in multiple sclerosis: an update.
Lancet Neurol 2019; 18: 198-210 [doi: 10.1016/S1474-4422(18)30451-4]
Filippi M, Brück W, Chard D, Fazekas F, Geurts JJG, Enzinger C, Hametner S, Kuhlmann T, Preziosa P, Rovira A, Schmierer K, Stadelmann C, Rocca MA, for the Attendees of the Correlation between Pathological and MRI findings in MS workshop.
Assessment of lesions on magnetic resonance imaging in multiple sclerosis: practical guidelines.
Brain 2019; 142: 1858-1975 [epub ahead of print 17 June 2019; doi: 10.1093/brain/awz144]
Filippi M, Preziosa P, Banwell BL, Barkhof F, Ciccarelli O, De Stefano N, Geurts JJG, Paul F, Reich DS, Toosy AT, Traboulsee A, Wattjes MP, Yousry TA, Gass A, Lubetzki C, Weinshenker BG, Rocca MA.
Changes in functional and structural brain connectome along the Alzheimer’s disease continuum.
Mol Psychiatr 2020; 25: 230-239 [epub ahead of print 9 May 2018; doi: 10.1038/s41380-018-0067-8]
Filippi M, Basaia S, Canu E, Imperiale F, Magnani G, Falautano M, Comi G, Falini A, Agosta F.
Longitudinal brain connectivity changes and clinical evolution in Parkinson’s disease.
Mol Psychiatr 2021;26: 5429-5440 [epub ahead of print 14 May 2020; doi: 10.1038/s41380-020-0770-0]
Filippi M, Basaia S, Sarasso E, Stojkovic T, Stankovic I, Fontana A, Tomic A, Piramide N, Stefanova E, Markovic V, Kostic VS, Agosta F.
Neural correlates of visuospatial processing in migraine: does the pain network help?
Mol Psychiatr 2021; 26: 6599–6608 [Epub ahead of print 9 Apr 2021; doi: 10.1038/s41380-021-01085-2]
Messina R, Meani A, Riccitelli GC, Colombo B, Filippi M, Rocca MA.
Early predictors of 9-year disability in pediatric multiple sclerosis.
Ann Neurol 2021; 89: 1011-1022 [Epub ahead of print 17 Feb 2021; doi: 10.1002/ana.26052]
De Meo E, Bonacchi R, Moiola L, Colombo B, Sangalli F, Zanetta C, Amato MP, Martinelli V, Rocca MA, Filippi M.
Performance of the 2017 and 2010 revised McDonald criteria in predicting MS diagnosis after a clinically isolated syndrome. A MAGNIMS Study.
Neurology 2022; 98: e1-e14 [Epub ahead of print 29 October 2021; doi: 10.1212/WNL.0000000000013016]
Filippi M, Preziosa P, Meani A, Dalla Costa G, Mesaros S, Drulovic J, Ivanovic J, Rovira A, Tintorè M, Montalban X, Ciccarelli O, Brownlee W, Miszkiel K, Enzinger C, Khalil M, Barkhof F, Strijbis EMM, Frederiksen JL, Cramer S, Fainardi E, Amato MP, Gasperini C, Ruggieri S, Martinelli V, Comi G, Rocca MA, for the MAGNIMS Study Group.

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