Lorenzo Piemonti

职业:
内分泌科医生
语言:
EN
IT

个人简介

Lorenzo Piemonti教授是IRCCS圣拉斐尔科学研究医院糖尿病和内分泌代谢疾病科医生,在Emanuele Bosi教授的指导下开展工作。

在IRCCS圣拉斐尔科学研究医院,Piemonti教授也是糖尿病研究所主任和人类胰岛移植项目负责人。但在学术领域,他是米兰圣拉斐尔生命健康大学的内分泌学副教授,也是布鲁塞尔自由大学的客座教授。

1994年,他从米兰大学医学院毕业。2000年,获得内分泌学和代谢紊乱相关疾病专业学位。2004年,他在同一所大学获得显微外科和实验外科专业学位。

Piemonti教授的临床活动涵盖临床内分泌学(甲状腺、肥胖等),重点关注所有临床形式的糖尿病、组织移植和再生医学。

在研究方面,Piemonti教授主要关注糖尿病和胰腺学,重点关注人胰岛移植模型和胰腺癌的生物学。此外,Piemonti教授的研究领域还包括β细胞置换、免疫耐受诱导策略、树突状细胞和干细胞生物学。

他以作者身份在国际期刊上发表了250多篇原创科研论文。H指数为61。Piemonti教授经常作为发言人和主持人参加国内外行业会议。

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出版物

最新出版物

Targeting CXCR1/2 Does Not Improve Insulin Secretion After Pancreatic Islet Transplantation: A Phase 3, Double-Blind, Randomized, Placebo-Controlled Trial in Type 1 Diabetes. Diabetes Care.
2020 Feb 4. pii: dc191480. doi: 10.2337/dc19-1480. [Epub ahead of print] PubMed PMID: 32019854.
Maffi P, Lundgren T, Tufveson G, Rafael E, Shaw JAM, Liew A, Saudek F, Witkowski P, Golab K, Bertuzzi F, Gustafsson B, Daffonchio L, Ruffini PA, Piemonti L; and the REP0211 Study Group; REP0211 Study Group.
Reduced PD-1 expression on circulating CXCR5(+) and CXCR5(-) FOXP3(+) Treg cells marks type 1 diabetes initiation in children.
Clin Immunol. 2019 Nov 30:108319. doi: 10.1016/j.clim.2019.108319. [Epub ahead of print] PubMed PMID: 31794865.
Vecchione A, Gerosa J, Di Fonte R, Jofra T, Pia CM, Napoleone V, Ippolito E, Galvani G, Ragogna F, Stabilini A, Bianconi E, Grogan P, Bonura C, Bonfanti R, Frontino G, Nano R, Melzi R, De Pellegrin M, Laurenzi A, Meschi F, Barera G, Rigamonti A, Indirli R, Bosi E, Piemonti L, Aiuti A, Battaglia M, Fousteri G.
The impact of proinflammatory cytokines on the β-cell regulatory landscape provides insights into the genetics of type 1 diabetes. Nat Genet
2019 Nov 1. doi: 10.1038/s41588-019-0524-6. [Epub ahead of print] PubMed PMID: 31676868.
Ramos-Rodríguez M, Raurell-Vila H, Colli ML, Alvelos MI, Subirana-Granés M, Juan-Mateu J, Norris R, Turatsinze JV, Nakayasu ES, Webb-Robertson BM, Inshaw JRJ, Marchetti P, Piemonti L, Esteller M, Todd JA, Metz TO, Eizirik DL, Pasquali L.
Pharmacological Targeting of GLUT1 to Control Autoreactive T Cell Responses
Int J Mol Sci 2019 Oct 8;20(19). pii: E4962. doi: 10.3390/ijms20194962. Review. PubMed PMID: 31597342; PubMed CentralPMCID: PMC6801424.
Di Dedda C, Vignali D, Piemonti L, Monti P.
Selective local irradiation improves islet engraftment and survival in intra-bone marrow islet transplantation
Cytotherapy. 2019 Aug 20. pii: S1465-3249(19)30821-7. doi: 10.1016/j.jcyt.2019.07.005. [Epub ahead of print] PubMed PMID: 31444049.
Pellegrini S, Cantarelli E, Citro A, Incerti E, Piemonti L§, Sordi V§.
Heterogeneity of human pancreatic islet isolation around Europe: results of a survey study
Transplantation. 2019 Jul 17. doi: 10.1097/TP.0000000000002777. [Epub ahead of print] PubMed PMID: 31365472.
Nano R, Kerr-Conte JA, Scholz H, Engelse M, Karlsson M, Saudek F, Bosco D, Antonioli B, Bertuzzi F, Johnson PRV, Ludwing B, Ling Z, De Paep DL, Keymeulen B, Pattou F, Berney T, Korsgren O, de Koning E, Piemonti L.
Islet Transplantation
South Dartmouth (MA): MDText.com, Inc.; 2000-.PubMed PMID: 25905200.
Piemonti L. In: Feingold KR, Anawalt B, Boyce A, Chrousos G, Dungan K, Grossman A, Hershman JM, Kaltsas G, Koch C, Kopp P, Korbonits M, McLachlan R, Morley JE, New M, Perreault L, Purnell J, Rebar R, Singer F, Trence DL, Vinik A, Wilson DP,
扩展阅读
Nothing Is Perfect, but We Can Do Better
Diabetes. 2019 Aug;68(8):1541-1543. doi: 10.2337/db19-0367. PubMed PMID: 31331988.
Nano R, Kerr-Conte JA, Bosco D, Karlsson M, Lavallard V, Melzi R, Gmyr V, Mercalli A, Berney T, Pattou F, Korsgren O, Piemonti L. Islets for Research.
CCL2/MCP-1 and CXCL12/SDF-1 BLOCKADE BY L-aptamers IMPROVE PANCREATIC ISLET ENGRAFTMENT AND SURVIVAL IN MOUSE
Am J Transplant. 2019 Jul 3. doi: 10.1111/ajt.15518. [Epub ahead of print] PubMed PMID: 31267721.
Citro A, Pellegrini S, Dugnani E, Eulberg D, Klussmann S, Piemonti L.
Human pancreatic islet threedimensional chromatin architecture provides insights into the genetics of type 2 diabetes
Nat Genet. 2019 Jul;51(7):1137-1148. doi: 10.1038/s41588-019-0457-0. Epub 2019 Jun 28. PubMed PMID: 31253982.
Miguel-Escalada I, Bonàs-Guarch S, Cebola I, Ponsa-Cobas J, Mendieta-Esteban J, Atla G, Javierre BM, Rolando DMY, Farabella I, Morgan CC, García-Hurtado J, Beucher A, Morán I, Pasquali L, Ramos- Rodríguez M, Appel EVR, Linneberg A, Gjesing AP, Witte DR, Pedersen O, Grarup N, Ravassard P, Torrents D, Mercader JM, Piemonti L, Berney T, de Koning EJP, Kerr-Conte J, Pattou F, Fedko IO, Groop L, Prokopenko I, Hansen T, Marti-Renom MA, Fraser P, Ferrer J.
Low-Carb and Ketogenic Diets in Type 1 and Type 2 Diabetes. Nutrients
2019 Apr 26; 11(5). pii: E962.doi: 10.3390/nu11050962. Review. PubMed PMID: 31035514
Bolla AM, Caretto A, Laurenzi A, Scavini M, Piemonti L.
Glucose metabolism during tumorigenesis in the genetic mouse model of pancreatic cancer
Acta Diabetol. 2019 Sep;56(9):1013-1022. doi: 10.1007/s00592-019-01335-4. Epub 2019 Apr 15.
Pasquale V, Dugnani E, Liberati D, Marra P, Citro A, Canu T, Policardi M, Valla L, Esposito A, Piemonti L.
Biofabrication of a vascularized islet organ for type 1 diabetes.
Biomaterials 2019 Apr;199:40-51. doi: 10.1016/j.biomaterials.2019.01.035. Epub 2019 Jan 24.
Citro A, Moser PT, Dugnani E, Rajab TK, Ren X, Evangelista-Leite D, Charest JM, Peloso A, Podesser BK, Manenti F, Pellegrini S, Piemonti L§, Ott HC§.
Inhibition of Eph/ephrin interaction with the small molecule UniPR500 improves glucose tolerance in healthy and insulin-resistant mice.
Pharmacol Res. 2019 Jan 6;141:319-330. doi: 10.1016/j.phrs.2019.01.011.
Giorgio C, Incerti M, Pala D, Russo S, Chiodelli P, Rusnati M, Cantoni AM, Di Lecce R, Barocelli E, Bertoni S, Ravassard P, Manenti F, Piemonti L, Ferlenghi F, Lodola A, Tognolini M.
Measurement of Autoantibodies to Gastric H+,K+-ATPase (ATP4A/B) Using a Luciferase Immunoprecipitation System (LIPS)
Methods Mol Biol. 2019;1901:113-131.
Lahner E, Marzinotto I, Brigatti C, Davidson H, Wenzlau J, Piemonti L, Annibale B, Lampasona V.
Diabetes-free survival after extended distal pancreatectomy and islet auto transplantation for benign or borderline/malignant lesions of the pancreas
Am J Transplant. 2019 Mar;19(3):920-928
Balzano G, Maffi P, Nano R, Mercalli A, Melzi R, Aleotti F, De Cobelli F, Magistretti P, Scavini M, Secchi A, Falconi M, Piemonti L.

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