Transplanted ovarian tissue in a sterile woman

Ovarian tissue may be transplanted at its site of origin or outside the pelvis (e.g., at the forearm or abdominal wall). Like harvesting, reimplantation can also be performed laparoscopically. Ovarian cortical fragments can be placed on the ovary or on a specially created peritoneal pocket in the pelvis and held in place without the use of sutures by fibrin glue. This technique guarantees the best results in terms of reproduction. The conception rate is around 30-40%. Full-term pregnancies from both spontaneous conception and assisted fertilization are reported. On the other hand, the tissue transplanted outside the pelvis is mainly aimed at restoring hormone production and, therefore, the treatment of menopausal symptoms or the induction of puberty in girls.

The team performs the operation laparoscopically, creating a "pocket" at the removed ovary in which they insert fragments of healthy ovarian tissue previously cryopreserved in liquid nitrogen at -196°. Once the tissue has resumed its normal activity (it will take 3-4 months), on the one hand, the ovarian hormonal activity will restart, with the reappearance of the menstrual cycle and benefits throughout the body (bone metabolism, thyroid function, cardiovascular wellbeing), and, on the other hand, new eggs will be produced that can be fertilized in vitro.